Refereed journal article or data article (A1)

α-Melanocyte-stimulating hormone regulates vascular NO availability and protects against endothelial dysfunction




List of AuthorsPetteri Rinne, Wendy Nordlund, Ilkka Heinonen, Anna-Maija Penttinen, Antti Saraste, Suvi T. Ruohonen, Satu Mäkelä, Laura Vähätalo, Katja Kaipio, Minying Cai, Victor J. Hruby, Saku Ruohonen, Eriika Savontaus

PublisherOXFORD UNIV PRESS

Publication year2013

JournalCardiovascular Research

Journal name in sourceCARDIOVASCULAR RESEARCH

Journal acronymCardiovasc Res

Number in series2

Volume number97

Issue number2

Start page360

End page368

Number of pages9

ISSN0008-6363

eISSN1755-3245

DOIhttp://dx.doi.org/10.1093/cvr/cvs335


Abstract

The present study identifies -MSH and endothelial MC1 receptors as a new signalling pathway contributing to the regulation of NO availability and vascular function. These findings suggest applicability of -MSH analogues for therapeutic use in pathological conditions that are characterized by vascular dysfunction.


Last updated on 2021-24-06 at 09:40