A1 Journal article – refereed
Universal platform for quantitative analysis of DNA transposition

List of Authors: Pajunen MI, Rasila TS, Happonen LJ, Lamberg A, Haapa-Paananen S, Kiljunen S, Savilahti H
Publication year: 2010
Journal: Mobile DNA
Journal name in source: MOBILE DNA
Journal acronym: MOBILE DNA-UK
Number in series: 24
Volume number: 1
Issue number: 24
Number of pages: 14
ISSN: 1759-8753

Conclusions: The established universal papillation assay platform should be widely applicable to a variety of mobile elements. It can be used for mechanistic studies to dissect transposition and provides a means to screen or scrutinise transposase mutants and genes encoding host factors. In succession, improved versions of transposition systems should yield better tools for molecular biology and offer versatile genome modification vehicles for many types of studies, including gene therapy and stem cell research.

Last updated on 2019-21-08 at 23:01