Refereed journal article or data article (A1)

Universal platform for quantitative analysis of DNA transposition




List of AuthorsPajunen MI, Rasila TS, Happonen LJ, Lamberg A, Haapa-Paananen S, Kiljunen S, Savilahti H

PublisherBIOMED CENTRAL LTD

Publication year2010

JournalMobile DNA

Journal name in sourceMOBILE DNA

Journal acronymMOBILE DNA-UK

Number in series24

Volume number1

Issue number24

Number of pages14

ISSN1759-8753

DOIhttp://dx.doi.org/10.1186/1759-8753-1-24

URLhttp://www.mobilednajournal.com/content/1/1/24


Abstract
Conclusions: The established universal papillation assay platform should be widely applicable to a variety of mobile elements. It can be used for mechanistic studies to dissect transposition and provides a means to screen or scrutinise transposase mutants and genes encoding host factors. In succession, improved versions of transposition systems should yield better tools for molecular biology and offer versatile genome modification vehicles for many types of studies, including gene therapy and stem cell research.


Last updated on 2021-24-06 at 09:47