A1 Journal article – refereed
Fatty acids as determinants of in-vivo lipid peroxidation: The EFFGE study in Eastern Finnish hypertensive and non-hypertensive subjects




List of Authors: Kaikkonen JE, Vilppo T, Asikainen J, Voutilainen S, Kurl S, Salonen JT
Publisher: INFORMA HEALTHCARE
Publication year: 2013
Journal: Annals of Medicine
Journal name in source: ANNALS OF MEDICINE
Journal acronym: ANN MED
Number in series: 5-6
Volume number: 45
Issue number: 5-6
Number of pages: 10
ISSN: 0785-3890

Abstract
Conclusions. We propose that elevated lipid peroxidation is associated with several risk factors of CVD, such as a low PUFA/SFA ratio, whereas the FA precursors of lipid peroxidation, i.e. omega-3 and omega-6 PUFAs are associated with attenuated F-2-IsoP levels. These findings provide mechanistic support for earlier observations linking PUFA to improved cardiovascular health.


Research Areas


Last updated on 2019-21-08 at 19:56