A1 Journal article – refereed
Environmental stimuli shape biofilm formation and the virulence of periodontal pathogens




List of Authors: Pöllänen M T, Paino A, Ihalin R
Publication year: 2013
Journal: International journal of molecular science
Journal name in source: International Journal of Molecular Sciences
Number in series: 8
Volume number: 14
Issue number: 8
Number of pages: 17
ISSN: 1422-0067

Abstract
Periodontitis is a common inflammatory disease affecting the tooth-supporting structures. It is initiated by bacteria growing as a biofilm at the gingival margin, and communication of the biofilms differs in health and disease. The bacterial composition of periodontitis-associated biofilms has been well documented and is under continual investigation. However, the roles of several host response and inflammation driven environmental stimuli on biofilm formation is not well understood. This review article addresses the effects of environmental factors such as pH, temperature, cytokines, hormones, and oxidative stress on periodontal biofilm formation and bacterial virulence. © 2013 by the authors; licensee MDPI, Basel, Switzerland.

Last updated on 2019-21-08 at 22:45