A1 Journal article – refereed
[F-18]Fluorination of an arylboronic ester using [F-18]selectfluor bis(triflate): application to 6-[F-18]fluoro-L-DOPA




List of Authors: Stenhagen ISR, Kirjavainen AK, Forsback SJ, Jorgensen CG, Robins EG, Luthra SK, Solin O, Gouverneur V
Publisher: ROYAL SOC CHEMISTRY
Publication year: 2013
Journal: Chemical Communications
Journal name in source: CHEMICAL COMMUNICATIONS
Journal acronym: CHEM COMMUN
Number in series: 14
Volume number: 49
Issue number: 14
Number of pages: 3
ISSN: 1359-7345

Abstract
The Ag-mediated electrophilic [F-18]fluorination of an arylboronic ester is reported. This new radiochemical transformation uses [F-18]selectfluor bis(triflate) in acetone. The process gave 6-[F-18]-fluoro-L-DOPA with a RCY of 19 +/- 12% and a specific activity of 2.6 +/- 0.3 GBq mu mol(-1).

Last updated on 2019-21-08 at 21:59