A1 Journal article – refereed
Metabolite Profiling and Cardiovascular Event Risk A Prospective Study of 3 Population-Based Cohorts




List of Authors: Wurtz P, Havulinna AS, Soininen P, Tynkkynen T, Prieto-Merino D, Tillin T, Ghorbani A, Artati A, Wang Q, Tiainen M, Kangas AJ, Kettunen J, Kaikkonen J, Mikkila V, Jula A, Kahonen M, Lehtimaki T, Lawlor DA, Gaunt TR, Hughes AD, Sattar N, Illig T, Adamski J, Wang TJ, Perola M, Ripatti S, Vasan RS, Raitakari OT, Gerszten RE, Casas JP, Chaturvedi N, Ala-Korpela M, Salomaa V
Publisher: LIPPINCOTT WILLIAMS & WILKINS
Publication year: 2015
Journal: Circulation
Journal name in source: CIRCULATION
Journal acronym: CIRCULATION
Volume number: 131
ISSN: 0009-7322

Abstract


Conclusions-Metabolite profiling in large prospective cohorts identified phenylalanine, monounsaturated fatty acids, and polyunsaturated fatty acids as biomarkers for cardiovascular risk. This study substantiates the value of high-throughput metabolomics for biomarker discovery and improved risk assessment.



Last updated on 2019-20-07 at 04:31