Eero Rissanen
MD, PhD, neurology consultant

Neurology (Department of Clinical Medicine)

eerris@utu.fi
+358 29 450 4746
+358 50 472 8599

Itäinen Pitkäkatu 4
Turku
Turku PET Centre PharmaCity
Office: 6006





Areas of expertise
Neurology; neuroimmunology; multiple sclerosis; neuroinflammation; PET; MRI

Biography

I am clinical neurologist and a clinical researher in Turku Univerity Hospital (Tyks) and University of Turku. As my main clinical duty in the Division of Clinical Neurosciences in Tyks, I have worked as the chief physician in the neurology outpatient polyclinic in Tyks Vakka-Suomi Hospital in Uusikaupunki since 2013. I attained my MD degree in 2005 and neurology consultant degree in 2011, both in the University of Turku.

Alongside my clinical duties, I have worked as a part time clinical researcher in professor Laura Airas's research group in Turku PET Centre and Division of Clinical Neurosciences in Tyks since 2009. I defended my doctoral thesis, entitled "Imaging neuroinflammation in progressive multiple sclerosis" in Turku University in 2015. Thereafter, I have continued as a part time postdoctoral researher in professor Airas's group.



Research

The main topic of my research has been the imaging of neuroinflammation in progressive multiple sclerosis, with the focus on activated microglia and adenosine A2A receptors. The fore mentioned targets can be visualized by the means of specific radioligands and positron emission tomography (PET). Recently, we have also been developing imaging and other biomarker methods for the evaluation of activated astrocytes. Neuroinflammation with astroglial activation (i.e. activation of microglia and astrocytes) is one of the hallmarks of disease pathology in many neuroinflammatory and neurodegenerative disorders. Thus, evaluating astroglial activation in vivo by the means of PET and advanced MR imaging will provide further understanding in the mechanisms and temporal evolution of these disease processes, and may provide new targets for developing disease modifying treatments in the future.

The work in our reseach group is highly multidisciplinary including collaboration with radiochemists, radiographers, mathematicians, physicists and clinical doctors as well as basic researchers with various backgrounds from biosciences.



Teaching

In clinical neurology as well as in clinical research, teaching is one of the core responsibilities, and at the same time a great privilege, for the senior doctors. I have participated in teaching of clinical neurology as a clinical teacher for the medical students in the neurology courses in Turku University in 2015, 2016, 2018 and 2019. I have also given several lectures in other university courses, such as in the Neurology for Neuroscientists course carried out by the Turku Brain and Mind Center. In addition, I have participated in numerous educational events as an invited speaker, the themes being mainly on clinical neuroimmunology and imaging of neuroinflammation.

In our research group, I am supervising master's and doctoral students alongside our primary investigator, professor Laura Airas.

I have also attained the subspecialty of Medical Education (The Finnish Medical Association) in 2018.



Publications
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Rituksimabi MS-taudin hoidossa (2019)
Duodecim
Airas L, Nylund M, Mannonen I, Sucksdorff M, Rissanen E
(
A1 Journal article – refereed)

Brain amyloid load and its associations with cognition and vascular risk factors in FINGER study (2018)
Neurology
Nina Kemppainen, Jarkko Johansson, Jarmo Teuho, Riitta Parkkola, Juho Joutsa, Tiia Ngandu, Alina Solomon, Ruth Stephen, Yawu Liu, Tuomo Hänninen, Teemu Paajanen, Tiina Laatikainen, Hilkka Soininen, Antti Jula, Johanna Rokka, Eero Rissanen, Tero Vahlberg, Julia Peltoniemi, Miia Kivipelto, Juha O. Rinne
(
A1 Journal article – refereed)

Evaluation of microglial activation in multiple sclerosis patients using positron emission tomography (2018)
Frontiers in Neurology
Laura Airas, Marjo Nylund, Eero Rissanen
(
A2 Review article in a scientific journal)

Microglial activation, white matter tract damage, and disability in MS (2018)
Neurology, Neuroimmunology and Neuroinflammation
Rissanen E, Tuisku J, Vahlberg T, Sucksdorff M, Paavilainen T, Parkkola R, Rokka J, Gerhard A, Hinz R, Talbot PS, Rinne JO, Airas L
(
A1 Journal article – refereed)

Positron emission tomography imaging in evaluation of MS pathology in vivo (2018)
Multiple Sclerosis
Heidi Högel, Eero Rissanen, Anna Vuorimaa, Laura Airas
(
A2 Review article in a scientific journal)

Serum glial fibrillary acidic protein correlates with multiple sclerosis disease severity (2018)
Multiple Sclerosis
Heidi Högel, Eero Rissanen, Christian Barro, Markus Matilainen, Marjo Nylund, Jens Kuhle, Laura Airas
(
A1 Journal article – refereed)

Severe neutropenia after rituximab-treatment of multiple sclerosis (2018)
Multiple Sclerosis and Related Disorders
Eero Rissanen, Kari Remes, Laura Airas
(
A1 Journal article – refereed)

Steroid-responsive encephalopathy with a peculiar CSF biomarker profile in an 89-year-old man (2018)
Oxford Medical Case Reports
Sipilä J., Rissanen E., Korpela J., Päivärinta M.
(
A1 Journal article – refereed)

Evaluation of the Effect of Fingolimod Treatment on Microglial Activation Using Serial PET Imaging in Multiple Sclerosis (2017)
Journal of Nuclear Medicine
Sucksdorff M, Rissanen E, Tuisku J, Nuutinen S, Paavilainen T, Rokka J, Rinne J, Airas L
(
A1 Journal article – refereed)

Imaging of microglial activation in MS using PET: Research use and potential future clinical application (2017)
Multiple Sclerosis
Airas L, Rissanen E, Rinne J
(
A2 Review article in a scientific journal)

In Vivo PET Imaging of Adenosine 2A Receptors in Neuroinflammatory and Neurodegenerative Disease (2017)
Contrast Media and Molecular Imaging
Anna Vuorimaa, Eero Rissanen, Laura Airas
(
A2 Review article in a scientific journal)

Neuroinflammation following traumatic brain injury: A positron emission tomography study (2017)
Brain Injury
Mehrbod Mohammadian, Jouni Tuisku, Jussi Hirvonen, Riitta Parkkola, Pekka Jokinen, Eero Rissanen, Olli Tenovuo
(
O2 Other)

Utilization of PET imaging in differential diagnostics between a tumefactive multiple sclerosis lesion and low-grade glioma (2016)
Multiple Sclerosis and Related Disorders
Tarkkonen A, Rissanen E, Tuokkola T, Airas L
(
A1 Journal article – refereed)

Automated reference region extraction and population-based input function for brain [11C]TMSX PET image analyses (2015)
Journal of Cerebral Blood Flow and Metabolism
Rissanen E, Tuisku J, Luoto P, Arponen E, Johansson J, Oikonen V, Parkkola R, Airas L, Rinne JO.
(
A1 Journal article – refereed)

Imaging neuroinflammation in multiple sclerosis using TSPO-PET (2015)
Clinical and Translational Imaging
Laura Airas, Eero Rissanen, Juha Rinne
(
A2 Review article in a scientific journal)

Imaging Neuroinflammation in Progressive Multiple Sclerosis (2015) Rissanen Eero
(
G5 Doctoral dissertation (article))

Kuvantaminen MS-taudissa (2015)
Lääkärilehti
Laura Airas, Eero Rissanen, Marcus Sucksdorff, Teemu Paavilainen, Timo Kurki, Juha Rinne
(
A2 Review article in a scientific journal)

Microglial activation correlates with disease progression in multiple sclerosis (2015) E. Rissanen, J. Tuisku, M. Gardberg, A.M. Dickens, M. Sucksdorff, J. Rokka, T. Paavilainen, R. Parkkola, J.O. Rinne, L. Airas
(
O2 Other)

Brain dopamine transporter binding and glucose metabolism in progressive supranuclear palsy-like creutzfeldt-jakob disease. (2014)
Case Reports in Neurology
Rissanen E, Kaasinen V, Sonninen P, Röyttä M, Päivärinta M
(
A1 Journal article – refereed)

Brain positron emission tomography scanning can be used to image pathological determinants of progressive multiple sclerosis (2014)
Multiple Sclerosis
Airas L, Rissanen E, Gardberg M, Sucksdorff M, Tuisku J, Rinne J
(
O2 Other)


Last updated on 2019-15-09 at 02:21