Urpo Lamminmäki
PhD

Associate Professor, Biotechnology / FM (Department of Biochemistry)

urplammi@utu.fi
+358 29 450 4587
+358 50 476 5557

Kiinamyllynkatu 10
Turku





Areas of expertise
Antibody engineering, Bioaffinity assays, in vitro diagnostics

Research

My research is largerly focused to recombinant antibodies and other bioaffinity molecules, techniques used to generate them and applications of these molecules in the diagnostics and drug development. Other reseach interests relate to the biomarkes of diseases.



Teaching

Methods and application of molecular biotechnology
Antibody and protein engineering techniques
Protein chemistry





Publications
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Array-in-well epitope mapping of phage-displayed antibodies (2018) Epitope Mapping Protocols Urpo Lamminmäki, Gaurav Batra, Petri Saviranta
(
A3 Book chapter)

Molecular tools for selective recovery and detection of lignin-derived molecules (2018)
Green Chemistry
Milla Salmela, Hanna Sanmark, Elena Efimova, Alexander Efimov, Vesa P. Hytönen, Urpo Lamminmäki, Suvi Santala, Ville Santala
(
A1 Journal article – refereed)

Array-in-well binding assay for multiparameter screening of phage displayed antibodies (2017)
Methods
Susan Pérez-Gamarra, Liisa Hattara, Gaurav Batra, Petri Saviranta, Urpo Lamminmäki
(
A1 Journal article – refereed)

Effect of DNA sequence of Fab fragment on yield characteristics and cell growth of E-coli (2017)
Scientific Reports
Kulmala A, Huovinen T, Lamminmaki U
(
A1 Journal article – refereed)

Non-competitive ELISA with broad specificity for microcystins and nodularins (2017)
Advances in Oceanography and Limnology
Sultana Akter, Markus Vehniäinen, Jussi Meriluoto, Lisa Spoof, Urpo Lamminmäki
(
A1 Journal article – refereed)

Rapid and Highly Sensitive Non-Competitive Immunoassay for Specific Detection of Nodularin (2017)
Microorganisms
Akter S, Vehniainen M, Kankaanpaa HT, Lamminmaki U
(
A1 Journal article – refereed)

A Nanoparticle-Lectin Immunoassay Improves Discrimination of Serum CA125 from Malignant and Benign Sources (2016)
Clinical Chemistry
Gidwani K, Huhtinen K, Kekki H, van Vliet S, Hynninen J, Koivuviita N, Perheentupa A, Poutanen M, Auranen A, Grenman S, Lamminmaki U, Carpen O, van Kooyk Y, Pettersson K
(
A1 Journal article – refereed)

Broad-Spectrum Noncompetitive Immunocomplex Immunoassay for Cyanobacterial Peptide Hepatotoxins (Microcystins and Nodularins) (2016)
Analytical Chemistry
Sultana Akter, Markus Vehniäinen, Lisa Spoof, Sonja Nybom, Jussi Meriluoto, and Urpo Lamminmäki
(
A1 Journal article – refereed)

Casamino acids facilitate the secretion of recombinant dengue virus serotype-3 envelope domain III in Pichia pastoris (2016)
BMC Biotechnology
Kaushik N, Rohila D, Arora U, Raut R, Lamminmaki U, Khanna N, Batra G
(
A1 Journal article – refereed)

Development of recombinant antibody-based enzyme-linked immunosorbent assay (ELISA) for the detection of skatole (2016)
Analytical Biochemistry
Janne Leivo, Joonas Mäkela, Jaana Rosenberg, Urpo Lamminmäki
(
A1 Journal article – refereed)

Identification and analysis of anti-HDL scFv-antibodies obtained from phage display based synthetic antibody library – Phage display derived HDL antibodies (2016)
Clinical Biochemistry
Priyanka Negi,Janita Lövgren,Päivi Malmi,Nina Sirkka,Jari Metso,Tuomas Huovinen,Eeva-Christine Brockmann,Kim Pettersson,Matti Jauhiainen,Urpo Lamminmäki
(
A1 Journal article – refereed)

Internalization of secreted antigen-targeted antibodies by the neonatal Fc receptor for precision imaging of the androgen receptor axis (2016)
Science Translational Medicine
Thorek DLJ, Watson PA, Lee SG, Ku AT, Bournazos S, Braun K, Kim K, Sjostrom K, Doran MG, Lamminmaki U, Santos E, Veach D, Turkekul M, Casey E, Lewis JS, Abou DS, van Voss MRH, Scardino PT, Strand SE, Alpaugh ML, Scher HI, Lilja H, Larson SM, Ulmert D
(
A1 Journal article – refereed)

Next generation sequencing of all variable loops of synthetic single framework scFv-Application in anti-HDL antibody selections (2016)
New Biotechnology
Lovgren J, Pursiheimo JP, Pyykko M, Salmi J, Lamminmaki U
(
A1 Journal article – refereed)

Recombinant antibodies for specific detection of clostridial [Fe-Fe] hydrogenases (2016)
Scientific Reports
Mangayil R, Karp M, Lamminmaki U, Santala V
(
A1 Journal article – refereed)

Role of lectin microarrays in cancer diagnosis (2016)
Proteomics
Parvez Syed, Kamlesh Gidwani, Henna Kekki, Janne Leivo, Kim Pettersson, Urpo Lamminmäki
(
A2 Review article in a scientific journal)

Structural basis for Myf and Psa fimbriae-mediated tropism of pathogenic strains of Yersinia for host tissues (2016)
Molecular Microbiology
Pakharukova N, Roy S, Tuittila M, Rahman MM, Paavilainen S, Ingars AK, Skaldin M, Lamminmäki U, Härd T, Teneberg S, Zavialov AV.
(
A1 Journal article – refereed)

Detection of cyanobacterial sxt genes and paralytic shellfish toxins in freshwater lakes and brackish waters on Åland Islands, Finland (2015)
Harmful Algae
Henna Savela, Lisa Spoof, Niina Perälä, Mikko Preede, Urpo Lamminmäki, Sonja Nybom, Kerstin Häggqvist, Jussi Meriluoto, Markus Vehniäinen
(
A1 Journal article – refereed)

Eph Receptors as Drug Targets: Single-Chain Antibodies and Beyond (2015)
Current Drug Targets
Lamminmaki U, Nikolov D, Himanen J
(
A1 Journal article – refereed)

Fast conversion of scFv to Fab antibodies using type IIs restriction enzymes (2015)
Journal of Immunological Methods
Sanmark H, Huovinen T, Matikka T, Pettersson T, Lahti M, Lamminmaki U
(
A1 Journal article – refereed)


Last updated on 2019-20-07 at 02:19