Pekka Taimen
MD, PhD

Adjunct Professor, Institute of Biomedicine (Institute of Biomedicine)
Researcher, Institute of Biomedicine (Institute of Biomedicine)

pepeta@utu.fi
+358 29 450 4524
+358 50 431 1353

Kiinamyllynkatu 10
Turku





Areas of expertise
pathology; histology; cell biology; prostate cancer

Biography

Pekka Taimen received his MD degree from the University of Turku in 2001 and defended his thesis at the Department of Pathology, University of Turku in 2004. In 2008-2009 PT worked as a postdoctoral fellow in the laboratory of Prof. Robert D. Goldman, Northwestern University Medical School, Chicago. Postdoctoral studies focusing on nuclear intermediate filament proteins called lamins were further continued as a junior group leader after returning back to Turku in early 2010. In 2011 PT received a specialist degree in Pathology and since then he has worked as a part-time specialist in the Pathology Division, Turku University Hospital with special focus on uropathology. From 2012 PT has worked as a Clinical lecturer in Pathology and for 2015-2019 as a part-time Academy of Finland Clinical Researcher. In late 2018 PT was appointed as a tenure track Assistant Professor of Molecular Pathology.



Research

Assistant Professor Pekka Taimen has 20 years of experience in cell and molecular biology as well as in translational research. The main focus of his research group is on human diseases caused by lamin mutations, such as cardiomyopathies and premature aging syndrome. More recently, PT has also actively worked on prostate and bladder cancer related projects including novel biomarkers, biobanking, patient derived cell lines and improved imaging techniques utilizing digital pathology and machine learning approaches.



Teaching

Pekka Taimen has more than 10 years of experience in teaching medical students at the Institute of Biomedicine, University of Turku. He has served first as a university teacher and from 2012 as a clinical lecturer. In 2015 PT received the Lecturer of the Year award in the Faculty of Medicine.



Publications
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IMPROD biparametric MRI in men with a clinical suspicion of prostate cancer (IMPROD Trial): Sensitivity for prostate cancer detection in correlation with whole-mount prostatectomy sections and implications for focal therapy (2019)
Journal of Magnetic Resonance Imaging
Merisaari H., Jambor I., Ettala O., Boström P.J., Montoya Perez I., Verho J., Kiviniemi A., Syvänen K., Kähkönen E., Eklund L., Pahikkala T., Vainio P., Saunavaara J., Aronen H.J., Taimen P.
(
A1 Journal article – refereed)

SORLA regulates endosomal trafficking and oncogenic fitness of HER2 (2019)
Nature Communications
Mika Pietilä, Pranshu Sahgal, Emilia Peuhu, Niklas Z. Jäntti, Ilkka Paatero, Elisa Närvä, Hussein Al-Akhrass, Johanna Lilja, Maria Georgiadou, Olav M. Andersen, Artur Padzik, Harri Sihto, Heikki Joensuu, Matias Blomqvist, Irena Saarinen, Peter. J. Boström, Pekka Taimen, Johanna Ivaska
(
A1 Journal article – refereed)

Urine cytology is a feasible tool for assessing erythematous bladder lesions after bacille Calmette-Guérin (BCG) treatment (2019)
BJU International
Nurminen P., Ettala O., Seppänen M., Taimen P., Boström P., Kaipia A.
(
A1 Journal article – refereed)

ANO7 is associated with aggressive prostate cancer (2018)
International Journal of Cancer
Kaikkonen E., Rantapero T., Zhang Q., Taimen P., Laitinen V., Kallajoki M., Jambulingam D., Ettala O., Knaapila J., Boström P., Wahlström G., Sipeky C., Pursiheimo J., Tammela T., Kellokumpu-Lehtinen P., Fey V., Maehle L., Wiklund F., Wei G., Schleutker J.
(
A1 Journal article – refereed)

C-11-acetate PET/MRI in bladder cancer staging and treatment response evaluation to neoadjuvant chemotherapy: a prospective multicenter study (ACEBIB trial) (2018) Antti Salminen, Ivan Jambor, Harri Merisaari, Otto Ettala, Johanna Virtanen, Ilmari Koskinen, Erik Veskimae, Jukka Sairanen, Pekka Taimen, Jukka Kemppainen, Heikki Minn, Peter J. Boström
(
A1 Journal article – refereed)

Intratumoral androgen levels are linked to TMPRSS2-ERG fusion in prostate cancer (2018)
Endocrine-Related Cancer
Knuuttila M, Mehmood A, Maki-Jouppila J, Ryberg H, Taimen P, Knaapila J, Ettala O, Bostrom PJ, Ohlsson C, Venalainen MS, Laiho A, Elo LL, Sipila P, Makela SI, Poutanen M
(
A1 Journal article – refereed)

Laminopatiat - harvinaisten sairauksien kasvava joukko (2018)
Duodecim
Virtanen L, Gullmets J, Heliö T, Taimen P
(
A2 Review article in a scientific journal)

New prostate cancer grade grouping system predicts survival after radical prostatectomy (2018)
Human Pathology
Andrew Erickson, Kevin Sandeman, Kanerva Lahdensuo, Stig Nordling, Markku Kallajoki, Heikki Seikkula, Anna Bützow, Hanna Vasarainen, Peter J. Boström, Pekka Taimen, Antti Rannikko, Tuomas Mirtti
(
A1 Journal article – refereed)

Pegylated and liposomal doxorubicin is associated with high mortality and causes limited cardiotoxicity in mice (2018)
BMC Research Notes
Christoffer Stark, Pekka Taimen, Timo Savunen, Juha Koskenvuo
(
A1 Journal article – refereed)

Prospective evaluation of 18F-FACBC PET/CT and PET/MRI versus multiparametric MRI in intermediate- to high-risk prostate cancer patients (FLUCIPRO trial) (2018)
European Journal of Nuclear Medicine and Molecular Imaging
Jambor I, Kuisma A, Kähkönen E, Kemppainen J, Merisaari H, Eskola O, Teuho J, Perez IM, Pesola M, Aronen HJ, Boström PJ, Taimen P, Minn H
(
A1 Journal article – refereed)

Radiomic features from pretreatment biparametric MRI predict prostate cancer biochemical recurrence: Preliminary findings (2018)
Journal of Magnetic Resonance Imaging
Rakesh Shiradkar, Soumya Ghose, Ivan Jambor, Pekka Taimen, Otto Ettala, Andrei S. Purysko, Anant Madabhushi
(
A1 Journal article – refereed)

The composition of prostate core matrisome in vivo and in vitro unveiled by mass spectrometric analysis (2018)
Prostate
Marjaana Ojalill, Pekka Rappu, Elina Siljamäki, Pekka Taimen, Peter Boström, Jyrki Heino
(
A1 Journal article – refereed)

Fitting methods for intravoxel incoherent motion imaging of prostate cancer on region of interest level: Repeatability and gleason score prediction (2017)
Magnetic Resonance in Medicine
Harri Merisaari, Parisa Movahedi, Ileana M. Perez, Jussi Toivonen, Marko Pesola, Pekka Taimen, Peter J. Boström, Tapio Pahikkala, Aida Kiviniemi, Hannu J. Aronen, Ivan Jambor
(
A1 Journal article – refereed)

Immunological tumor status may predict response to neoadjuvant chemotherapy and outcome after radical cystectomy in bladder cancer (2017)
Scientific Reports
Tervahartiala M, Taimen P, Mirtti T, Koskinen I, Ecke T, Jalkanen S, Bostrom PJ
(
A1 Journal article – refereed)

Increased FGFRL1 expression is associated with prostate cancer progression (2017)
Cancer Research
Yu L., Toriseva M., Erickson A., Seikkula H., Nurmi M., Taimen P., Boström P., Mirtti T., Alanen K., Kallajoki M., Tuomela J., Nees M., Härkönen P.
(
O2 Other)

Internal epithelia in Drosophila display rudimentary competence to form cytoplasmic networks of transgenic human vimentin (2017)
FASEB Journal
Gullmets J, Torvaldson E, Lindqvist J, Imanishi SY, Taimen P, Meinander A, Eriksson JE
(
A1 Journal article – refereed)

Nestin contributes to skeletal muscle homeostasis and regeneration (2017)
Journal of Cell Science
Lindqvist J, Torvaldson E, Gullmets J, Karvonen H, Nagy A, Taimen P, Eriksson JE
(
A1 Journal article – refereed)

Novel Biparametric MRI and Targeted Biopsy Improves Risk Stratification in Men With a Clinical Suspicion of Prostate Cancer (IMPROD Trial) (2017)
Journal of Magnetic Resonance Imaging
Jambor I, Bostrom PJ, Taimen P, Syvanen K, Kahkonen E, Kallajoki M, Perez IM, Kauko T, Matomaki J, Ettala O, Merisaari H, Kiviniemi A, Dean PB, Aronen HJ
(
A1 Journal article – refereed)

Radiomic features for prostate cancer detection on MRI differ between the transition and peripheral zones: Preliminary findings from a multi-institutional study (2017) Ginsburg SB, Algohary A, Pahwa S, Gulani V, Ponsky L, Aronen HJ, Boström PJ, Böhm M, Haynes AM, Brenner P, Delprado W, Thompson J, Pulbrock M, Taimen P, Villani R, Stricker P, Rastinehad AR, Jambor I, Madabhushi A
(
A1 Journal article – refereed)

Deleterious assembly of the lamin A/C mutant p.S143P causes ER stress in familial dilated cardiomyopathy (2016)
Journal of Cell Science
West G, Gullmets J, Virtanen L, Li SP, Keinanen A, Shimi T, Mauermann M, Helio T, Kaartinen M, Ollila L, Kuusisto J, Eriksson JE, Goldman RD, Herrmann H, Taimen P
(
A1 Journal article – refereed)


Last updated on 2019-16-07 at 02:23