Heidi Korhonen
University teacher

University Teacher, Laboratory of Organic Chemistry and Chemical Biology (Department of Chemistry)

hejoli@utu.fi
+358 29 450 3181
+358 46 920 5524

Vatselankatu 2
Turku
Arcanum
Office: K217



Areas of expertise
Oligonucleotide synthesis; organic synthesis; mechanistic studies of RNA phosphodiester bond; DNA templated ligation; DNA nanostructures

Biography

University of Turku, Department of Chemistry, university teacher (2018-)

University of Turku, Department of Chemistry, university lecturer (2014-2018)

University of Durham, UK, post doctoral fellow (2013-2014)

University of Turku, Department of Chemistry, university teacher (2011-2013)

University of Turku, Department of Chemistry, PhD in organic chemistry, 2011



Research

My research interests are:

Mechanistic studies of RNA phosphodiester bond and other biologically active phosphate esters.

Nucleoside phosphorylation.

Enzyme-free, DNA-templated ligation reactions.

DNA nanostructures.



Teaching

I´m one of the teachers in courses:

KEMI6135 Experimental Methods for Chemists

KEMI6111 Laboratory Experiments for Chemists I, Intermediate Level

KEMI6307 Chemistry, Laboratory Experiments, Intermediate Level




Publications

DNA-Templated N(Me)-Alkoxyamine Glycosylation (2018)
Organic Letters
Tommi Österlund, Heidi Korhonen, Pasi Virta
(
A1 Journal article – refereed)

A procedure for the preparation and isolation of nucleoside-5 '-diphosphates (2015)
Beilstein Journal of Organic Chemistry
Heidi J. Korhonen, Hannah L. Bolt, David R. W. Hodgson
(
A1 Journal article – refereed)

Metal ion‑promoted cleavage of nucleoside diphosphosugars: a model for reactions of phosphodiester bonds in carbohydrates (2015)
Journal of Biological Inorganic Chemistry
Meisa Dano, Marjukka Elmeranta, David R.W.Hodgson, Juho Jaakkola, Heidi Korhonen, Satu Mikkola
(
A1 Journal article – refereed)

PPN pyrophosphate: A New Reagent for the Preparation of Nucleoside Triphosphates (2015)
Phosphorus, Sulfur, and Silicon and the Related Elements
Heidi J. Korhonen, Hannah L. Bolt, Leyre Vicente-Gines, Daniel C. Perks, David R. W. Hodgson
(
A1 Journal article – refereed)

The Role of Protein-Ligand Contacts in Allosteric Regulation of the Escherichia coli Catabolite Activator Protein (2015)
Journal of Biological Chemistry
Philip D. Townsend, Thomas L. Rodgers, Laura C. Glover, Heidi J. Korhonen, Shane A. Richards, Lucy J. Colwell, Ehmke Pohl, Mark R. Wilson, David R. W. Hodgson, Tom C. B. McLeish, Martin J. Cann
(
A1 Journal article – refereed)

Phosphate analogues in the dissection of mechanism (2014)
Current Opinion in Chemical Biology
Heidi J Korhonen, Louis P Conway, David RW Hodgson
(
A2 Review article in a scientific journal)

ss(LG) values in mechanistic studies on the transesterification of RNA models and their application in a metal ion complex promoted transesterification (2013)
Journal of Physical Organic Chemistry
Heidi Korhonen, Nicholas H Williams, Satu Mikkola
(
A2 Review article in a scientific journal)

There is no universal mechanism for the cleavage of RNA model compounds in the presence of metal ion catalysts (2013)
Organic and Biomolecular Chemistry
Korhonen H, Koivusalo T, Toivola S, Mikkola S
(
A1 Journal article – refereed)

The Mechanism of Cleavage and Isomerisation of RNA Promoted by an Efficient Dinuclear Zn2+ Complex (2012)
Chemistry - A European Journal
Korhonen H, Mikkola S, Williams NH
(
A1 Journal article – refereed)


Last updated on 2019-25-05 at 02:24