Olli Raitakari
MD/PhD


olli.raitakari@utu.fi
+358 29 450 2304
Kiinamyllynkatu 10
Turku





Areas of expertise
cardiovascular and metabolic diseases; risk factors; vascular epidemiology; genetic epidemiology; epidemiology; dietary intervention; cohort studies; follow-up studies

Biography

EDUCATION AND DEGREES
 
2001   Docent in Clinical Physiology
1997-1999  Postdoc training, Royal Prince Alfred Hospital, Sydney, Australia
1997   Docent in Epidemiology
1996   Specialist in Clinical Physiology 
1995   Doctorate, PhD
1989   Licentiate in Medicine, MD

CURRENT POSITIONS

2017-                 Professor in Cardiovascular Medicine, Director of the Research Centre of Applied and 
                          Preventive Cardiovascular Medicine, University of Turku, Finland                         

 

PAST POSITIONS

2012-2016                          Academy Professor, University of Turku

2007-2016                          Professor in Cardiovascular Medicine (part time), University of Turku

2007-2008                          Senior Scientist Grant, Academy of Finland

2004-2016                          Chief Physician, Department of Clinical Physiology and Nuclear Medicine, Turku
                                           University Hospital (leave of absence 2012-2016)

2002-2004                          Consultant in Clinical Physiology and Nuclear Medicine, Turku University Hospital

2002 (1 mo)                        Head of Nuclear Medicine Department, Turku University Hospital

2000-2003 (3 mo)               Head of Clinical Physiology Department, Turku University Hospital

2000-2005                          Senior Fellow Post, Academy of Finland

1998-2000                          Postdoctoral Research Post, Academy of Finland

1996-1997                          Consultant in Clinical Physiology, Turku University Hospital

1991-1996                          Positions as Resident in Clinical Chemistry, Nuclear Medicine, and Clinical 
                                           Physiology, Turku University Hospital

1988-1990                          Positions as General Practioner and Resident in Internal Medicine or Surgery




Research

Evidence suggest that many non-communicable disease outcomes have roots in childhood and may even stem of adverse ancestral exposures. Improved knowledge how various ancestral and early-life exposures lead to adult disease outcomes is essential in developing better preventive practices and policies that lead to improved public health. My mission has been to contribute to this knowledge-base by working in epidemiologic cohort studies with follow-up from childhood to adulthood. I am the Principal Investigator of the Cardiovascular Risk in Young Finns Study (YFS), the largest study in Europe with a follow-up of cardiovascular risk factors from childhood to adulthood. I am also the Director of the STRIP Study, which is a leading long-term pediatric dietary intervention study testing the hypothesis that modifying the fat quality diet will have beneficial effects on cardiovascular risk early in life. During the past years, I have organized several field studies in these cohorts, and introduced novel technologies, such as imaging studies, genetic epidemiology methods and metabolomics approaches in these unique population resources. Our research has contributed to the understanding of pre-clinical development of atherosclerosis in children and young adults, including the effects of diet, life-style, metabolic risk factors, psychological traits and psychosocial factors, inflammation, hormones and genetic markers. For example, by applying non-invasive imaging methods in the Young Finns Study, we have demonstrated that exposure to adverse lipids, elevated blood pressure and obesity in childhood is related to atherosclerosis development in adulthood (JAMA 2003). Subsequent work stemmed from this initial observation has led to numerous original publications that have shown in detail how exposure to a large range of aetiogenic factors early in life contribute to the development of cardio-metabolic outcomes in adulthood. For example, by pooling international i3C Consortium data, we have demonstrated that overweight or obese children who became non-obese by adulthood had similar risks of many cardio-metabolic adult outcomes as individuals who were never obese (NEJM 2011). Thus, the results of our studies have clearly demonstrated that individual’s exposure to various stressors in early life is contributing to his/her adult phenotype and disease risk. The results have had significant impact on preventive practices. As a concrete demonstration of the international recognition and impact of my team’s work, many of our studies are widely cited in all updated paediatric guidelines on cardiovascular prevention both in Europe and in US.



Publications
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Association of Childhood Oral Infections With Cardiovascular Risk Factors and Subclinical Atherosclerosis in Adulthood (2019) Pirkko J. Pussinen, Susanna Paju, Jaana Koponen, Jorma S. A. Viikari, Leena Taittonen, Tomi Laitinen, David P. Burgner, Mika Kähönen, Nina Hutri-Kähönen, Olli T. Raitakari, Markus Juonala
(
A1 Journal article – refereed)

Common Genetic Variation in Relation to Brachial Vascular Dimensions and Flow-Mediated Vasodilation (2019)
Circulation: Genomic and Precision Medicine
Dorr M, Hamburg NM, Muller C, Smith NL, Gustafsson S, Lehtimaki T, Teumer A, Zeller T, Li X, Lind L, Raitakari OT, Volker U, Blankenberg S, McKnight B, Morris AP, Kahonen M, Lemaitre RN, Wild PS, Nauck M, Volzke H, Munzel T, Mitchell GF, Psaty BM, Lindgren CM, Larson MG, Felix SB, Ingelsson E, Lyytikainen LP, Herrington D, Benjamin EJ, Schnabel RB, Schnabel RB
(
B1 Journal article)

Coronary heart disease risk factor levels in eastern and western Finland from 1980 to 2011 in the cardiovascular risk in Young Finns study (2019)
Atherosclerosis
Vähämurto L, Pahkala K, Magnussen CG, Hutri-Kähönen N, Kähönen M, Laitinen T, Taittonen L, Tossavainen P, Lehtimäki T, Jokinen E, Telama R, Rönnemaa T, Viikari J, Juonala M, Raitakari OT
(
A1 Journal article – refereed)

Discovery of mitochondrial DNA variants associated with genome-wide blood cell gene expression: a population-based mtDNA sequencing study (2019)
Human Molecular Genetics
Jaakko Laaksonen, Ilkka Seppälä, Emma Raitoharju, Nina Mononen, Leo-Pekka Lyytikäinen, Melanie Waldenberger, Thomas Illig, Maija Lepistö, Henrikki Almusa, Pekka Ellonen, Nina Hutri-Kähönen, Markus Juonala, Mika Kähönen, Olli Raitakari, Jukka T. Salonen, Terho Lehtimäki
(
A1 Journal article – refereed)

Gene-environment correlations in parental emotional warmth and intolerance: genome-wide analysis over two generations of the Young Finns Study (2019)
Journal of Child Psychology and Psychiatry
Henrik Dobewall, Kateryna Savelieva, Ilkka Seppälä, Ariel Knafo‐Noam, Christian Hakulinen, Marko Elovainio,
Liisa Keltikangas‐Järvinen, Laura Pulkki‐Råback, Olli T. Raitakari, Terho Lehtimäki, Mirka Hintsanen

(
A1 Journal article – refereed)

Genetic and environmental perturbations lead to regulatory decoherence (2019)
eLife
Amanda Lea, Meena Subramaniam, Arthur Ko, Terho Lehtimäki, Emma Raitoharju, Mika Kähönen, Ilkka Seppälä, Nina Mononen, Olli T Raitakari, Mika Ala-Korpela, Päivi Pajukanta, Noah Zaitlen, Julien F Ayroles
(
A1 Journal article – refereed)

Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations (2019)
Nature Genetics
Sakornsakolpat P, Prokopenko D, Lamontagne M, Reeve NF, Guyatt AL, Jackson VE, Shrine N, Qiao DD, Bartz TM, Kim DK, Lee MK, Latourelle JC, Li XN, Morrow JD, Obeidat M, Wyss AB, Bakke P, Barr RG, Beaty TH, Belinsky SA, Brusselle GG, Crapo JD, de Jong K, DeMeo DL, Fingerlin TE, Gharib SA, Gulsvik A, Hall IP, Hokanson JE, Kim WJ, Lomas DA, London SJ, Meyers DA, O'Connor GT, Rennard SI, Schwartz DA, Sliwinski P, Sparrow D, Strachan DP, Tal-Singer R, Tesfaigzi Y, Vestbo J, Vonk JM, Yim JJ, Zhou XB, Bosse Y, Manichaikul A, Lahousse L, Silverman EK, Boezen HM, Wain LV, Tobin MD, Hobbs BD, Cho; SpiroMeta Consortium & International COPD Genetics Consortium
(
A1 Journal article – refereed)

Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences (2019)
Nature Genetics
Linner RK, Biroli P, Kong E, Meddens FW, Wedow R, Fontana MA, Lebreton M, Tino SP, Abdellaoui A, Hammerschlag AR, Nivard MG, Okbay A, Rietveld CA, Timshel PN, Trzaskowski M, Vlaming R, Zund CL, Bao YC, Buzdugan L, Caplin AH, Chen CY, Eibich P, Fontanillas P, Gonzalez JR, Joshi PK, Karhunen V, Kleinman A, Levin RZ, Lill CM, Meddens GA, Muntane G, Sanchez-Roige S, Rooij FJ, Taskesen E, Wu Y, Zhang FT, Agee M, Alipanahi B, Bell RK, Bryc K, Elson SL, Furlotte NA, Huber KE, Litterman NK, McCreight JC, McIntyre MH, Mountain JL, Northover CAM, Pitts SJ, Sathirapongsasuti JF, Sazonova OV, Shelton JF, Shringarpure S, Tian C, Tung JY, Vacic V, Wilson CH, Agbessi M, Ahsan H, Alves I, Andiappan A, Awadalla P, Battle A, Beutner F, Bonder MJ, Boomsma DI, Christiansen M, Claringbould A, Deelen P, Esko T, Fave MJ, Franke L, Frayling T, Gharib SA, Gibson G, Heijmans B, Hemani G, Jansen R, Kahonen M, Kalnapenkis A, Kasela S, Kettunen J, Kim Y, Kirsten H, Kovacs P, Krohn K, Kronberg-Guzman J, Kukushkina V, Kutalik Z, Lee B, Lehtimaki T, Loeffler M, Marigorta UM, Metspalu A, Milani L, Montgomery GW, Mueller-Nurasyid M, Nauck M, Penninx B, Perola M, Pervjakova N, Pierce B, Powell J, Prokisch H, Psaty BM, Raitakari O, Ring S, Ripatti S, Rotzchke O, Rueger S, Saha A, Scholz M, Schramm K, Seppala I, Stumvoll M, Sullivan P, Hoen PB, Teumer A, Thiery J, Tong L, Tonjes A, van Dongen J, van Meurs J, Verlouw J, Visscher PM, Volker U, Vosa U, Westra HJ, Yaghootkar H, Yang J, Zeng B, Lee JJ, Pers TH, Turley P, Chen GB, Emilsson V, Oskarsson S, Pickrell JK, Thom K, Timshel P, Ahluwalia TS, Bacelis J, Baumbach C, Bjornsdottir G, Brandsma JH, Concas MP, Derringer J, Furlotte NA, Galesloot TE, Girotto G, Gupta R, Hall LM, Harris SE, Hofer E, Horikoshi M, Huffman JE, Kaasik K, Kalafati IP, Kong A, Lahti J, Lee SJD, Leeuw C, Lind PA, Lindgren KO, Liu T, Mangino M, Marten J, Mihailov E, Miller MB, Most PJD, Oldmeadow C, Payton A, Pervjakova N, Peyrot WJ, Qian Y, Raitakari O, Rueedi R, Salvi E, Schmidt B, Schraut KE, Shi J, Smith AV, Poot RA, Pourcain B, Teumer A, Thorleifsson G, Verweij N, Vuckovic D, Wellmann J, Westra HJ, Yang JY, Zhao W, Zhu ZH, Alizadeh BZ, Amin N, Bakshi A, Baumeister SE, Biino G, Bonnelykke K, Boyle PA, Campbell H, Cappuccio FP, Davies G, De Neve JE, Deloukas P, Demuth I, Ding J, Eibich P, Eisele L, Eklund N, Evans DM, Faul JD, Feitosa MF, Forstner AJ, Gandin I, Gunnarsson B, Halldorsson BV, Harris TB, Heath AC, Hocking LJ, Holliday EG, Homuth G, Horan MA, Hottenga JJ, Jager PL, Jugessur A, Kaakinen MA, Kahonen M, Kanoni S, Keltigangas-Jarvinen L, Kiemeney LALM, Kolcic I, Koskinen S, Kraja AT, Kroh M, Kutalik Z, Latvala A, Launer LJ, Lebreton MP, Levinson DF, Lichtenstein P, Lichtner P, Liewald DCM, Loukola A, Madden PA, Magi R, Maki-Opas T, Marioni RE, Marques-Vidal P, McMahon G, Meisinger C, Meitinger T, Milaneschi Y, Milani L, Montgomery GW, Myhre R, Nelson CP, Nyholt DR, Ollier WER, Palotie A, Paternoster L, Pedersen NL, Petrovic KE, Porteous DJ, Raikkonen K, Ring SM, Robino A, Rostapshova O, Rudan I, Rustichini A, Salomaa V, Sanders AR, Sarin AP, Schmidt H, Scott RJ, Smith BH, Smith JA, Staessen JA, Steinhagen-Thiessen E, Strauch K, Terracciano A, Tobin MD, Ulivi S, Vaccargiu S, Quaye L, Venturini C, Vinkhuyzen AAE, Volker U, Voelzke H, Vonk JM, Vozzi D, Waage J, Ware EB, Willemsen G, Attia JR, Bennett DA, Berger K, Bertram L, Bisgaard H, Boomsma DI, Borecki IB, Bultmann U, Chabris CF, Cucca F, Cusi D, Deary J, Dedoussis GV, Duijn CM, Eriksson JG, Franke B, Franke L, Gasparini P, Gejman PV, Gieger C, Grabe HJ, Gratten J, Gudnason V, Harst PD, Hayward C, Hinds DA, Hoffmann W, Hypponen E, Iacono WG, Jacobsson B, Jarvelin MR, Jockel KH, Kaprio J, Kardia SLR, Lehtimaki T, Lehrer SF, Magnusson PKE, Martin NG, Mcgue M, Metspalu A, Pendleton N, Penninx B, Perola M, Pirastu N, Pirastu M, Polasek O, Posthuma D, Power C, Province MA, Samani NJ, Schlessinger D, Schmidt R, Sorensen TIA, Spector TD, Stefansson K, Thorsteinsdottir U, Thurik AR, Timpson NJ, Tiemeier H, Tung JY, Uitterlinden AG, Vitart V, Vollenweider P, Weir DR, Wilson JF, Wright AF, Conley DC, Krueger RF, Smith GD, Laibson DI, Medland SE, Yang J, Johannesson M, Visscher PM, Esko T, Koellinger PD, Cesarini D, Benjamin DJ, Auton A, Boardman JD, Clark DW, Conlin A, Dolan CC, Fischbacher U, Groenen PJF, Harris KM, Hasler G, Hofman A, Ikram MA, Jain S, Karlsson R, Kessler RC, Kooyman M, MacKillop J, Mannikko M, Morcillo-Suarez C, McQueen MB, Schmidt KM, Smart MC, Sutter M, Thurik AR, Uitterlinden AG, White J, de Wit H, Yang J, Bertram L, Boomsma DI, Esko T, Fehr E, Hinds DA, Johannesson M, Kumari M, Laibson D, Magnusson PKE, Meyer MN, Navarro A, Palmer AA, Pers TH, Posthuma D, Schunk D, Stein MB, Svento R, Tiemeier H, Timmers PRHJ, Turley P, Ursano RJ, Wagner GG, Wilson JF, Gratten J, Lee JJ, Cesarini D, Benjamin DJ, Koellinger PD, Beauchamp JP, Cesarini D, Lee JJ, Koellinger PD, Benjamin DJ, Beauchamp JP, Gratten J
(
A1 Journal article – refereed)

Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits (2019)
European Journal of Human Genetics
Hottenga J., Iorio A., Kors J., Linneberg A., Ford I., Hansen T., Harris T., Heckbert S., Silva Aldana C., Sinagra G., Sinner M., Soliman E., MacFarlane P., Meitinger T., Nelson C., Raitakari O., Gasparini P., Alonso A., Jamshidi Y., Gudnason V., Uitterlinden A., Stoll M., Waldenberger M., van Duijn C., Samani N., Peters A., Ulivi S., Sotoodehnia N., Kanters J., Kääb S., Munroe P., Lehtimäki T., Isaacs A., van der Harst P., de Bakker P., Jukema J., Stricker B., Wilson J., de Geus E., van Setten J., Verweij N., Trompet S., Arking D., Mbarek H., Niemeijer M., Hall L., Grarup N., Gandin I., Brody J., Müller-Nurasyid M., Mei H., Lyytikäinen L., Hemerich D., Warren H., Smith A., Robino A., Prins B., Eijgelsheim M., Caulfield M., Boomsma D., Asselbergs F.
(
A1 Journal article – refereed)

Genomics of 1 million parent lifespans implicates novel pathways and common diseases and distinguishes survival chances (2019)
eLife
Timmers PRHJ, Mounier N, Lall K, Fischer K, Ning Z, Feng X, Bretherick AD, Clark DW; eQTLGen Consortium, Shen X, Esko T, Kutalik Z, Wilson JF, Joshi PK
(
A1 Journal article – refereed)

Health endowment and later-life outcomes in the labour market: Evidence using genetic risk scores and reduced-form models (2019)
SSM - Population Health
Pehkonen J., Viinikainen J., Böckerman P., Pitkänen N., Lehtimäki T., Raitakari O.
(
A1 Journal article – refereed)

IDO activity forecasts obesity in females in 10-year follow-up study: the Cardiovascular Risk in Young Finns study (2019)
Thrombosis Research
P. Niinisalo, O.T.Raitakari, M. Kähonen, J. Viikari, M. Juonala, R. Kaaja
(
O2 Other)

IMI - Myopia Genetics Report (2019)
Investigative Ophthalmology & Visual Science
Tedja MS, Haarman AEG, Meester-Smoor MA, Kaprio J, Mackey DA, Guggenheim JA, Hammond CJ, Verhoeven VJM, Klaver CCW, Bailey-Wilson JE, Baird PN, Veluchamy AB, Biino G, Burdon KP, Campbell H, Chen LJ, Cheng CY, Chew EY, Craig JE, Cumberland PM, Deangelis MM, Delcourt C, Ding XH, van Duijn CM, Evans DM, Fan Q, Fossarello M, Foster PJ, Gharahkhani P, Iglesias AI, Guol XB, Haller T, Han XK, Hayward C, He MG, Hewitt AW, Hoang Q, Hysi PG, Igo RP, Iyengar SK, Jonas JB, Kahonen M, Khawaja AP, Klein BE, Klein R, Lass JH, Lee K, Lehtimaki T, Lewis D, Li Q, Li SM, Lyytikainen LP, MacGregor S, Martin NG, Meguro A, Metspalu A, Middlebrooks C, Miyake M, Mizuki N, Musolf A, Nickels S, Oexle K, Pang CP, Parssinen O, Paterson AD, Pfeiffer N, Polasek O, Rahi JS, Raitakari O, Rudan I, Sahebjada S, Saw SM, Stambolian D, Simpson CL, Tai ES, Tideman JWL, Tsujikawa A, Verhoeven VJM, Vitart V, Wang NL, Wedenoja J, Wei WB, Williams C, Williams KM, Wilson JF, Wojciechowski R, Wang YX, Yamashiro K, Yam JCS, Yap MKH, Yazar S, Yip SP, Young TL, Zhou XT, Young TL, Yip SP, Zhou XT, Yazar S
(
A1 Journal article – refereed)

Increased High-Density Lipoprotein Levels Associated with Age-Related Macular Degeneration Evidence from the EYE-RISK and European Eye Epidemiology Consortia (2019)
Ophthalmology: Journal of The American Academy of Ophthalmology
Johanna M. Colijn, Anneke I. den Hollander, Ayse Demirkan, Audrey Cougnard-Grégoire, Timo Verzijden, Eveline Kersten, Magda A. Meester-Smoor, Benedicte M.J. Merle, Grigorios Papageorgiou, Shahzad Ahmad, Monique T. Mulder, Miguel Angelo Costa, Pascale Benlian, Geir Bertelsen, Alain M. Bron, Birte Claes, Catherine Creuzot-Garcher, Maja Gran Erke, Sascha Fauser, Paul J. Foster, Christopher J. Hammond, Hans-Werner Hense, Carel B. Hoyng, Anthony P. Khawaja, Jean-Francois Korobelnik, Stefano Piermarocchi, Tatiana Segato, Rufino Silva, Eric H. Souied, Katie M. Williams, Cornelia M. van Duijn, Cécile Delcourt, Caroline C.W. Klaver; for the European Eye Epidemiology Consortium and EYE-RISK Consortium
(
A1 Journal article – refereed)

Low-saturated-fat and low-cholesterol diet does not alter pubertal development and hormonal status in adolescents (2019)
Acta Paediatrica
Sergey Sadov, Helena E. Virtanen, Katharina M. Main, Anna‐Maria Andersson, Anders Juul, Antti Jula, Olli T. Raitakari, Katja Pahkala, Harri Niinikoski, Jorma Toppari
(
A1 Journal article – refereed)

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors (2019)
Nature Genetics
Warrington N.M., Beaumont R.N., Horikoshi M., Day F.R., Helgeland Ø., Laurin C., Bacelis J., Peng S., Hao K., Feenstra B., Wood A.R., Mahajan A., Tyrrell J., Robertson N.R., Rayner N.W., Qiao Z., Moen G.-H., Vaudel M., Marsit C.J., Chen J., Nodzenski M., Schnurr T.M., Zafarmand M.H., Bradfield J.P., Grarup N., Kooijman M.N., Li-Gao R., Geller F., Ahluwalia T.S., Paternoster L., Rueedi R., Huikari V., Hottenga J.-J., Lyytikäinen L.-P., Cavadino A., Metrustry S., Cousminer D.L., Wu Y., Thiering E., Wang C.A., Have C.T., Vilor-Tejedor N., Joshi P.K., Painter J.N., Ntalla I., Myhre R., Pitkänen N., van Leeuwen E.M., Joro R., Lagou V., Richmond R.C., Espinosa A., Barton S.J., Inskip H.M., Holloway J.W., Santa-Marina L., Estivill X., Ang W., Marsh J.A., Reichetzeder C., Marullo L., Hocher B., Lunetta K.L., Murabito J.M., Relton C.L., Kogevinas M., Chatzi L., Allard C., Bouchard L., Hivert M.-F., Zhang G., Muglia L.J., Heikkinen J., Morgen C.S., van Kampen A.H.C., van Schaik B.D.C., Mentch F.D., Langenberg C., Luan J., Scott R.A., Zhao J.H., Hemani G., Ring S.M., Bennett A.J., Gaulton K.J., Fernandez-Tajes J., van Zuydam N.R., Medina-Gomez C., de Haan H.G., Rosendaal F.R., Kutalik Z., Marques-Vidal P., Das S., Willemsen G., Mbarek H., Müller-Nurasyid M., Standl M., Appel E.V.R., Fonvig C.E., Trier C., van Beijsterveldt C.E.M., Murcia M., Bustamante M., Bonas-Guarch S., Hougaard D.M., Mercader J.M., Linneberg A., Schraut K.E., Lind P.A., Medland S.E., Shields B.M., Knight B.A., Chai J.-F., Panoutsopoulou K., Bartels M., Sánchez F., Stokholm J., Torrents D., Vinding R.K., Willems S.M., Atalay M., Chawes B.L., Kovacs P., Prokopenko I., Tuke M.A., Yaghootkar H., Ruth K.S., Jones S.E., Loh P.-R., Murray A., Weedon M.N., Tönjes A., Stumvoll M., Michaelsen K.F., Eloranta A.-M., Lakka T.A., van Duijn C.M., Kiess W., Körner A., Niinikoski H., Pahkala K., Raitakari O.T., Jacobsson B., Zeggini E., Dedoussis G.V., Teo Y.-Y., Saw S.-M., Montgomery G.W., Campbell H., Wilson J.F., Vrijkotte T.G.M., Vrijheid M., de Geus E.J.C.N., Hayes M.G., Kadarmideen H.N., Holm J.-C., Beilin L.J., Pennell C.E., Heinrich J., Adair L.S., Borja J.B., Mohlke K.L., Eriksson J.G., Widén E.E., Hattersley A.T., Spector T.D., Kähönen M., Viikari J.S., Lehtimäki T., Boomsma D.I., Sebert S., Vollenweider P., Sørensen T.I.A., Bisgaard H., Bønnelykke K., Murray J.C., Melbye M., Nohr E.A., Mook-Kanamori D.O., Rivadeneira F., Hofman A., Felix J.F., Jaddoe V.W.V., Hansen T., Pisinger C., Vaag A.A., Pedersen O., Uitterlinden A.G., Järvelin M.-R., Power C., Hyppönen E., Scholtens D.M., Lowe W.L., Jr, Davey Smith G., Timpson N.J., Morris A.P., Wareham N.J., Hakonarson H., Grant S.F.A., Frayling T.M., Lawlor D.A., Njølstad P.R., Johansson S., Ong K.K., McCarthy M.I., Perry J.R.B., Evans D.M., Freathy R.M.; EGG Consortium
(
A1 Journal article – refereed)

Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids (2019)
Nature Genetics
Bentley AR, Sung YJ, Brown MR, Winkler TW, Kraja AT, Ntalla I, Schwander K, Chasman DI, Lim E, Deng X, Guo XQ, Liu JM, Lu YC, Cheng CY, Sim X, Vojinovic D, Huffman JE, Musani SK, Li CW, Feitosa MF, Richard MA, Noordam R, Baker J, Chen GJ, Aschard H, Bartz TM, Ding JZ, Dorajoo R, Manning AK, Rankinen T, Smith AV, Tajuddin SM, Zhao W, Graff M, Alver M, Boissel M, Chai JF, Chen X, Divers J, Evangelou E, Gao C, Goel A, Hagemeijer Y, Harris SE, Hartwig FP, He MA, Horimoto ARVR, Hsu FC, Hung YJ, Jackson AU, Kasturiratne A, Komulainen P, Kuhnel B, Leander K, Lin KH, Luan JA, Lyytikainen LP, Matoba N, Nolte IM, Pietzner M, Prins B, Riaz M, Robino A, Said MA, Schupf N, Scott RA, Sofer T, Stancakova A, Takeuchi F, Tayo BO, van der Most PJ, Varga TV, Wang TD, Wang YJ, Ware EB, Wen WQ, Xiang YB, Yanek LR, Zhang WH, Zhao JH, Adeyemo A, Afaq S, Amin N, Amini M, Arking DE, Arzumanyan Z, Aung T, Ballantyne C, Barr RG, Bielak LF, Boerwinkle E, Bottinger EP, Broeckel U, Brown M, Cade BE, Campbell A, Canouil M, Charumathi S, Chen YDI, Christensen K, Concas MP, Connell JM, de las Fuentes L, de Silva HJ, de Vries PS, Doumatey A, Duan Q, Eaton CB, Eppinga RN, Faul JD, Floyd JS, Forouhi NG, Forrester T, Friedlander Y, Gandin I, Gao H, Ghanbari M, Gharib SA, Gigante B, Giulianini F, Grabe HJ, Gu CC, Harris TB, Heikkinen S, Heng CK, Hirata M, Hixson JE, Ikram MA, Jia YC, Joehanes R, Johnson C, Jonas JB, Justice AE, Katsuya T, Khor CC, Kilpelainen TO, Koh WP, Kolcic I, Kooperberg C, Krieger JE, Kritchevsky SB, Kubo M, Kuusisto J, Lakka TA, Langefeld CD, Langenberg C, Launer LJ, Lehne B, Lewis CE, Li YZ, Liang JJ, Lin S, Liu CT, Liu JJ, Liu K, Loh M, Lohman KK, Louie T, Luzzi A, Magi R, Mahajan A, Manichaikul AW, McKenzie CA, Meitinger T, Metspalu A, Milaneschi Y, Milani L, Mohlke KL, Momozawa Y, Morris AP, Murray AD, Nalls MA, Nauck M, Nelson CP, North KE, O'Connell JR, Palmer ND, Papanicolau GJ, Pedersen NL, Peters A, Peyser PA, Polasek O, Poulter N, Raitakari OT, Reiner AP, Renstrom F, Rice TK, Rich SS, Robinson JG, Rose LM, Rosendaal FR, Rudan I, Schmidt CO, Schreiner PJ, Scott WR, Sever P, Shi Y, Sidney S, Sims M, Smith JA, Snieder H, Starr JM, Strauch K, Stringham HM, Tan NYQ, Tang H, Taylor KD, Teo YY, Tham YC, Tiemeier H, Turner ST, Uitterlinden AG, van Heemst D, Waldenberger M, Wang HM, Wang L, Wang LH, Wei WB, Williams CA, Wilson G, Wojczynski MK, Yao J, Young K, Yu CZ, Yuan JM, Zhou J, Zonderman AB, Becker DM, Boehnke M, Bowden DW, Chambers JC, Cooper RS, de Faire U, Deary IJ, Elliott P, Esko T, Farrall M, Franks PW, Freedman BI, Froguel P, Gasparini P, Gieger C, Horta BL, Juang JMJ, Kamatani Y, Kammerer CM, Kato N, Kooner JS, Laakso M, Laurie CC, Lee IT, Lehtimaki T, Magnusson PKE, Oldehinkel AJ, Penninx BWJH, Pereira AC, Rauramaa R, Redline S, Samani NJ, Scott J, Shu XO, van der Harst P, Wagenknecht LE, Wang JS, Wang YX, Wareham NJ, Watkins H, Weir DR, Wickremasinghe AR, Wu TC, Zeggini E, Zheng W, Bouchard C, Evans MK, Gudnason V, Kardia SLR, Liu YM, Psaty BM, Ridker PM, van Dam RM, Mook-Kanamori DO, Fornage M, Province MA, Kelly TN, Fox ER, Hayward C, van Duijn CM, Tai ES, Wong TY, Loos RJF, Franceschini N, Rotter JI, Zhu XF, Bierut LJ, Gauderman WJ, Rice K, Munroe PB, Morrison AC, Rao DC, Rotimi CN, Cupples LA
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A1 Journal article – refereed)

Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity (2019)
Nature Communications
Kilpeläinen T.O., Bentley A.R., Noordam R., Sung Y.J., Schwander K., Winkler T.W., Jakupović H., Chasman D.I., Manning A., Ntalla I., Aschard H., Brown M.R., de las Fuentes L., Franceschini N., Guo X., Vojinovic D., Aslibekyan S., Feitosa M.F., Kho M., Musani S.K., Richard M., Wang H., Wang Z., Bartz T.M., Bielak L.F., Campbell A., Dorajoo R., Fisher V., Hartwig F.P., Horimoto A.R.V.R., Li C., Lohman K.K., Marten J., Sim X., Smith A.V., Tajuddin S.M., Alver M., Amini M., Boissel M., Chai J.F., Chen X., Divers J., Evangelou E., Gao C., Graff M., Harris S.E., He M., Hsu F.-C., Jackson A.U., Zhao J.H., Kraja A.T., Kühnel B., Laguzzi F., Lyytikäinen L.-P., Nolte I.M., Rauramaa R., Riaz M., Robino A., Rueedi R., Stringham H.M., Takeuchi F., van der Most P.J., Varga T.V., Verweij N., Ware E.B., Wen W., Li X., Yanek L.R., Amin N., Arnett D.K., Boerwinkle E., Brumat M., Cade B., Canouil M., Chen Y.-D.I., Concas M.P., Connell J., de Mutsert R., de Silva H.J., de Vries P.S., Demirkan A., Ding J., Eaton C.B., Faul J.D., Friedlander Y., Gabriel K.P., Ghanbari M., Giulianini F., Gu C.C., Gu D., Harris T.B., He J., Heikkinen S., Heng C.-K., Hunt S.C., Ikram M.A., Jonas J.B., Koh W.-P., Komulainen P., Krieger J.E., Kritchevsky S.B., Kutalik Z., Kuusisto J., Langefeld C.D., Langenberg C., Launer L.J., Leander K., Lemaitre R.N., Lewis C.E., Liang J., Alizadeh B.Z., Boezen H.M., Franke L., Navis G., Rots M., Swertz M., Wolffenbuttel B.H.R., Wijmenga C., Liu J., Mägi R., Manichaikul A., Meitinger T., Metspalu A., Milaneschi Y., Mohlke K.L., Mosley T.H., Jr., Murray A.D., Nalls M.A., Nang E.-E.K., Nelson C.P., Nona S., Norris J.M., Nwuba C.V., O’Connell J., Palmer N.D., Papanicolau G.J., Pazoki R., Pedersen N.L., Peters A., Peyser P.A., Polasek O., Porteous D.J., Poveda A., Raitakari O.T., Rich S.S., Risch N., Robinson J.G., Rose L.M., Rudan I., Schreiner P.J., Scott R.A., Sidney S.S., Sims M., Smith J.A., Snieder H., Sofer T., Starr J.M., Sternfeld B., Strauch K., Tang H., Taylor K.D., Tsai M.Y., Tuomilehto J., Uitterlinden A.G., van der Ende M.Y., van Heemst D., Voortman T., Waldenberger M., Wennberg P., Wilson G., Xiang Y.-B., Yao J., Yu C., Yuan J.-M., Zhao W., Zonderman A.B., Becker D.M., Boehnke M., Bowden D.W., de Faire U., Deary I.J., Elliott P., Esko T., Freedman B.I., Froguel P., Gasparini P., Gieger C., Kato N., Laakso M., Lakka T.A., Lehtimäki T., Magnusson P.K.E., Oldehinkel A.J., Penninx B.W.J.H., Samani N.J., Shu X.-O., van der Harst P., Van Vliet-Ostaptchouk J.V., Vollenweider P., Wagenknecht L.E., Wang Y.X., Wareham N.J., Weir D.R., Wu T., Zheng W., Zhu X., Evans M.K., Franks P.W., Gudnason V., Hayward C., Horta B.L., Kelly T.N., Liu Y., North K.E., Pereira A.C., Ridker P.M., Tai E.S., van Dam R.M., Fox E.R., Kardia S.L.R., Liu C.-T., Mook-Kanamori D.O., Province M.A., Redline S., van Duijn C.M., Rotter J.I., Kooperberg C.B., Gauderman W.J., Psaty B.M., Rice K., Munroe P.B., Fornage M., Cupples L.A., Rotimi C.N., Morrison A.C., Rao D.C., Loos R.J.F.; Lifelines Cohort Study
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A1 Journal article – refereed)

New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries (2019)
Nature Genetics
Shrine N, Guyatt AL, Erzurumluoglu AM, Jackson VE, Hobbs BD, Melbourne CA, Batini C, Fawcett KA, Song K, Sakornsakolpat P, Li XN, Boxall R, Reeve NF, Obeidat M, Zhao JH, Wielscher M, Weiss S, Kentistou KA, Cook JP, Sun BB, Zhou J, Hui J, Karrasch S, Imboden M, Harris SE, Marten J, Enroth S, Kerr SM, Surakka I, Vitart V, Lehtimaki T, Allen RJ, Bakke PS, Beaty TH, Bleecker ER, Bosse Y, Brandsma CA, Chen ZM, Crapo JD, Danesh J, DeMeo DL, Dudbridge F, Ewert R, Gieger C, Gulsvik A, Hansell AL, Hao K, Hoffman JD, Hokanson JE, Homuth G, Joshi PK, Joubert P, Langenberg C, Li X, Li LM, Lin K, Lind L, Locantore N, Luan JA, Mahajan A, Maranville JC, Murray A, Nickle DC, Packer R, Parker MM, Paynton ML, Porteous DJ, Prokopenko D, Qiao DD, Rawal R, Runz H, Sayers I, Sin DD, Smith BH, Artigas MS, Sparrow D, Tal-Singer R, Timmers PRHJ, Van den Berge M, Whittaker JC, Woodruff PG, Verges-Armstrong LM, Troyanskaya OG, Raitakari OT, Kahonenn M, Polasek O, Gyllensten U, Rudan I, Deary IJ, Probst-Hensch NM, Schulz H, James AL, Wilson JF, Stubbe B, Zeggini E, Jarvelin MR, Wareham N, Silverman EK, Hayward C, Morris AP, Butterworth AS, Scott RA, Walters RG, Meyers DA, Cho MH, Strachan DP, Hall IP, Tobin MD, Wain LV, Tobin MD, Wain LV, Strachan DP, Hall IP
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A1 Journal article – refereed)

Parent-Child-Relationship Quality Predicts Offspring Dispositional Compassion in Adulthood: A Prospective Follow-Up Study Over Three Decades (2019)
Developmental Psychology
Hintsanen Mirka, Gluschkoff Kia, Dobewall Henrik, Cloninger C. Robert, Keltner Dacher, Saarinen Aino, Wesolowska Karolina, Volanen Salla-Maarit, Raitakari Olli T., Pulkki-Råback Laura
(
A1 Journal article – refereed)


Last updated on 2019-23-07 at 02:21