Markus Vehniäinen


Biotechnology / DI (Department of Biochemistry)

marvehni@utu.fi







Research
Environmental diagnostic development. Includes monitoring toxic compounds in water environment and food safety diagnotics.

Publications

First report of cyanobacterial paralytic shellfish toxin biosynthesis genes and paralytic shellfish toxin production in Polish freshwater lakes (2017)
Advances in Oceanography and Limnology
Henna Savela, Lisa Spoof, Niina Höysniemi, Markus Vehniäinen, Joanna Mankiewicz-Boczek, Tomasz Jurczak, Mikolaj Kokociński, Jussi Meriluoto
(
A1 Journal article – refereed)

Non-competitive ELISA with broad specificity for microcystins and nodularins (2017)
Advances in Oceanography and Limnology
Sultana Akter, Markus Vehniäinen, Jussi Meriluoto, Lisa Spoof, Urpo Lamminmäki
(
A1 Journal article – refereed)

Rapid and Highly Sensitive Non-Competitive Immunoassay for Specific Detection of Nodularin (2017)
Microorganisms
Akter S, Vehniainen M, Kankaanpaa HT, Lamminmaki U
(
A1 Journal article – refereed)

Broad-Spectrum Noncompetitive Immunocomplex Immunoassay for Cyanobacterial Peptide Hepatotoxins (Microcystins and Nodularins) (2016)
Analytical Chemistry
Sultana Akter, Markus Vehniäinen, Lisa Spoof, Sonja Nybom, Jussi Meriluoto, and Urpo Lamminmäki
(
A1 Journal article – refereed)

Quantity of the dinoflagellate sxtA4 gene and cell density correlates with paralytic shellfish toxin production in Alexandrium ostenfeldii blooms (2016)
Harmful Algae
Henna Savela, Kirsi Harju, Lisa Spoof, Elin Lindehoff, Jussi Meriluoto, Markus Vehniäinen, Anke Kremp
(
A1 Journal article – refereed)

Detection of cyanobacterial sxt genes and paralytic shellfish toxins in freshwater lakes and brackish waters on Åland Islands, Finland (2015)
Harmful Algae
Henna Savela, Lisa Spoof, Niina Perälä, Mikko Preede, Urpo Lamminmäki, Sonja Nybom, Kerstin Häggqvist, Jussi Meriluoto, Markus Vehniäinen
(
A1 Journal article – refereed)

Phage display aided improvement of a unique prostate-specific antigen (PSA) antibody unreactive with Lys(145)-Lys(146) internally cleaved forms (2015)
Journal of Immunological Methods
Ferdhos Khan Liton, Mari T. Peltola, Markus Vehniäinen, Erica Kuusela, Tiina Pettersson, Urpo Lamminmäki, Kim Pettersson, Eeva-Christine Brockmann
(
A1 Journal article – refereed)

Rapid quantification of mcyB copy numbers on dry chemistry PCR chips and predictability of microcystin concentrations in freshwater environments (2014)
Harmful Algae
Henna Savela, Markus Vehniäinen, Lisa Spoof, Sonja Nybom, Jussi Meriluoto, Urpo Lamminmäki
(
A1 Journal article – refereed)

Aphanizomenon gracile (Nostocales), a cylindrospermopsin-producing cyanobacterium in Polish lakes (2013)
Environmental Science and Pollution Research
Kokocinski M, Mankiewicz-Boczek J, Jurczak T, Spoof L, Meriluoto J, Rejmonczyk E, Hautala H, Vehniäinen M, Pawelczyk J, Soininen J
(
A1 Journal article – refereed)

Multiresidue Detection of Fluoroquinolones: Specificity Engineering of a Recombinant Antibody with Oligonucleotide-Directed Mutagenesis (2013)
Journal of Agricultural and Food Chemistry
Leivo J, Lamminmäki U, Lövgren T, Vehniäinen M
(
A1 Journal article – refereed)

Quantitative PCR detection and improved sample preparation of microcystin-producing Anabaena, Microcystis and Planktothrix (2013)
Ecotoxicology and Environmental Safety
Hautala H, Lamminmäki U, Spoof L, Nybom S, Meriluoto J, Vehniäinen M
(
A1 Journal article – refereed)

Two ScFv antibody libraries derived from identical VLVH framework with different binding site designs display distinct binding profiles (2013)
Protein Engineering, Design and Selection
Huovinen T, Syrjanpää M, Sanmark H, Brockmann EC, Azhayev A, Wang Q, Vehniäinen M, Lamminmäki U
(
A1 Journal article – refereed)

Directed antibody-engineering techniques and their applications in food immunoassays (2011)
Trends in Analytical Chemistry
Markus V, Janne L, Urpo L
(
A1 Journal article – refereed)

Engineering of a broad-specificity antibody: Detection of eight fluoroquinolone antibiotics simultaneously (2011)
Analytical Biochemistry
Leivo J, Chappuis C, Lamminmaki U, Lovgren T, Vehniainen M
(
A1 Journal article – refereed)

Oligovalent Fab Display on M13 Phage Improved by Directed Evolution (2010)
Molecular Biotechnology
Huovinen T, Sanmark H, Yla-Pelto J, Vehniainen M, Lamminmaki U
(
A1 Journal article – refereed)

Use of high-capacity surface with oriented recombinant antibody fragments in a 5-min immunoassay for thyroid-stimulating hormone (2010)
Analytical Biochemistry
Brockmann EC, Vehniäinen M, Pettersson K
(
A1 Journal article – refereed)


Last updated on 2019-06-06 at 02:19