Hidehiro Iida
PhD in Physics from Univ of Tsukuba, PhD in Medical science from Tohoku Univ

Professor, PET Basic Operations (Turku PET Centre)

hidehiro.iida@utu.fi







Areas of expertise
Instrumentation and modeling in PET, SPECT and medical imaging

Biography

Dr.
Hidehiro Iida has received PhD in Physics (Experimental Nuclear Physics) by the nuclear reaction mechanism in 1984, in which 2nd Born approximation formulation was verified based on hyper-polarized proton accelerated beams introducing (p,t) reactions. He has also contributed to develop a unique position-sensitive detector. He then joined a team at Research Institute for Brain and Blood Vessels, Akita, Japan, to develop a clinical PET scanner for quantitative assessment of cerebral and cardiovascular blood flow and metabolism. He lead an activity to develop three kinds of PET scanners which are for clinical use, including the Dual PET tomograph which scans both brain and heart simultaneously. He has also contributed to develop novel methodologies to quantitate regional myocardial perfusion, oxydative metabolism, which have been considered the gold standard in assesing in clinical populations. He then moved to National Cerebral and Cardiovascular Center - Research Institute, as a Director of Department of Investigated Radiology, in 1999. He and his colleagues developed a novel animal disease models of stroke, and cardiovascular diseases, together with the non-invasive methodologies to investigate their pathophysiology in PET, SPECT and MRI. He also contributed to make software and radio-labeled ligan producing devives to be approved as medical devices. They have been utilized in >400 clinical hospitals. He has an appointment to Turku PET Centre, and University of Turku in January, 2018, and continues to develop/improve the clinical methodology for assessing biological/physiological functional parametric images in vivo.  



Research

Dr.
Hidehiro Iida’s primary interest is the non-invasive imaging of
bio-physiological functions and molecular processes using PET, SPECT and MRI modalities.
He has been working on instrumentation and kinetic modeling-based
methodologies. and contributed to develop several methods to quantitatively
assess tissue perfusion, oxidative metabolism and other functions, in brain,
heart and other organs. Some of those techniques have been utilized in a number
of clinical researches as a gold standard, and also in clinical practice in
patients with cerebral and cardiovascular diseases.



Teaching

Interest areas in teaching are as follows:

1. PET, SPECT and MR instrumentation

2. Mathematical modeling of biological processes to interprete the sequential PET, SPECT and MR images as an application of the inverse problem

3. To learn pathophysiology from PET, SPECT and MR images.  



Publications
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A DETERMINATION OF THE REGIONAL BRAIN BLOOD PARTITION-COEFFICIENT OF WATER USING DYNAMIC POSITRON EMISSION TOMOGRAPHY (1989)
Journal of Cerebral Blood Flow and Metabolism
IIDA H, KANNO I, MIURA S, MURAKAMI M, TAKAHASHI K, UEMURA K
(
A1 Journal article – refereed)

DESIGN AND EVALUATION OF HEADTOME-IV, A WHOLE-BODY POSITRON EMISSION TOMOGRAPH (1989)
IEEE Transactions on Nuclear Science
IIDA H, MIURA S, KANNO I, MURAKAMI M, TAKAHASHI K, UEMURA K, HIROSE Y, AMANO M, YAMAMOTO S, TANAKA K
(
A1 Journal article – refereed)

RADIOSYNTHESIS OF O-15-LABELED HYDROGEN-PEROXIDE (1989)
Journal of Labelled Compounds and Radiopharmaceuticals
TAKAHASHI K, MURAKAMI M, HAGAMI E, SASAKI H, KONDO Y, MIZUSAWA S, NAKAMICHI H, IIDA H, MIURA S, KANNO I, UEMURA K
(
A1 Journal article – refereed)

2-F-18 PHENYLALANINE AND 3-F-18 TYROSINE - SYNTHESIS AND PRELIMINARY DATA OF TRACER KINETICS (1988)
Journal of Labelled Compounds and Radiopharmaceuticals
MURAKAMI M, TAKAHASHI K, KONDO Y, MIZUSAWA S, NAKAMICHI H, SASAKI H, HAGAMI E, IIDA H, KANNO I, MIURA S, UEMURA K
(
A1 Journal article – refereed)

ANATOMICAL ADJUSTMENTS IN BRAIN POSITRON EMISSION TOMOGRAPHY USING CT IMAGES (1988)
Journal of Computer Assisted Tomography
MIURA S, KANNO I, IIDA H, MURAKAMI M, TAKAHASHI K, SASAKI H, INUGAMI A, SHISHIDO F, OGAWA T, UEMURA K
(
A1 Journal article – refereed)

EVALUATION OF REGIONAL DIFFERENCES OF TRACER APPEARANCE TIME IN CEREBRAL TISSUES USING [O-15]WATER AND DYNAMIC POSITRON EMISSION TOMOGRAPHY (1988)
Journal of Cerebral Blood Flow and Metabolism
IIDA H, HIGANO S, TOMURA N, SHISHIDO F, KANNO I, MIURA S, MURAKAMI M, TAKAHASHI K, SASAKI H, UEMURA K
(
A1 Journal article – refereed)

MEASUREMENT OF ABSOLUTE MYOCARDIAL BLOOD-FLOW WITH (H2O)-O-15 AND DYNAMIC POSITRON-EMISSION TOMOGRAPHY - STRATEGY FOR QUANTIFICATION IN RELATION TO THE PARTIAL-VOLUME EFFECT (1988)
Circulation
IIDA H, KANNO I, TAKAHASHI A, MIURA S, MURAKAMI M, TAKAHASHI K, ONO Y, SHISHIDO F, INUGAMI A, TOMURA N, HIGANO S, FUJITA H, SASAKI H, NAKAMICHI H, MIZUSAWA S, KONDO Y, UEMURA K, UEMURA K
(
A1 Journal article – refereed)

OXYGEN EXTRACTION FRACTION AT MAXIMALLY VASODILATED TISSUE IN THE ISCHEMIC BRAIN ESTIMATED FROM THE REGIONAL CO2 RESPONSIVENESS MEASURED BY POSITRON EMISSION TOMOGRAPHY (1988)
Journal of Cerebral Blood Flow and Metabolism
KANNO I, UEMURA K, HIGANO S, MURAKAMI M, IIDA H, MIURA S, SHISHIDO F, INUGAMI A, SAYAMA I
(
A1 Journal article – refereed)

THE COMPARATIVE SYNTHESIS OF F-18 FLUOROPHENYLALANINES BY ELECTROPHILIC SUBSTITUTION WITH F-18-F2 AND F-18-ACOF (1988)
Journal of Labelled Compounds and Radiopharmaceuticals
MURAKAMI M, TAKAHASHI K, KONDO Y, MIZUSAWA S, NAKAMICHI H, SASAKI H, HAGAMI E, IIDA H, KANNO I, MIURA S, UEMURA K
(
A1 Journal article – refereed)

A SYSTEM FOR CEREBRAL BLOOD-FLOW MEASUREMENT USING AN (H2O)-O-15 AUTORADIOGRAPHIC METHOD AND POSITRON EMISSION TOMOGRAPHY (1987)
Journal of Cerebral Blood Flow and Metabolism
KANNO I, IIDA H, MIURA S, MURAKAMI M, TAKAHASHI K, SASAKI H, INUGAMI A, SHISHIDO F, UEMURA K
(
A1 Journal article – refereed)

A BGO DETECTOR UNIT FOR A STATIONARY HIGH-RESOLUTION POSITRON EMISSION TOMOGRAPH (1986)
Journal of Computer Assisted Tomography
YAMAMOTO S, MIURA S, IIDA H, KANNO I
(
A1 Journal article – refereed)

A SIMULATION STUDY OF A METHOD TO REDUCE POSITRON-ANNIHILATION SPREAD DISTRIBUTIONS USING A STRONG MAGNETIC-FIELD IN POSITRON EMISSION TOMOGRAPHY (1986)
IEEE Transactions on Nuclear Science
IIDA H, KANNO I, MIURA S, MURAKAMI M, TAKAHASHI K, UEMURA K
(
A1 Journal article – refereed)

DEADTIME CORRECTION METHOD USING RANDOM COINCIDENCE FOR PET (1986)
Journal of Nuclear Medicine
YAMAMOTO S, AMANO M, MIURA S, IIDA H, KANNO I
(
A1 Journal article – refereed)

ERROR ANALYSIS OF A QUANTITATIVE CEREBRAL BLOOD-FLOW MEASUREMENT USING (H2O)-O-15 AUTORADIOGRAPHY AND POSITRON EMISSION TOMOGRAPHY, WITH RESPECT TO THE DISPERSION OF THE INPUT FUNCTION (1986)
Journal of Cerebral Blood Flow and Metabolism
IIDA H, KANNO I, MIURA S, MURAKAMI M, TAKAHASHI K, UEMURA K
(
A1 Journal article – refereed)

DESIGN AND EVALUATION OF A POSITRON EMISSION TOMOGRAPH - HEADTOME-III (1985)
Journal of Computer Assisted Tomography
KANNO I, MIURA S, YAMAMOTO S, IIDA H, MURAKAMI M, TAKAHASHI K, UEMURA K
(
A1 Journal article – refereed)

CONSTRUCTION OF A SIMPLE FOCAL-PLANE DETECTOR WITH HIGH POSITION RESOLUTION (1984)
Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
IIDA H, AOKI Y, YAGI K, MATOBA M
(
A1 Journal article – refereed)

ANALYZING POWERS AND CROSS-SECTIONS FOR (P,D) REACTIONS ON NUCLEI OF N=50-82 (1983)
Nuclear Physics A
AOKI Y, IIDA H, NAGANO K, TOBA Y, YAGI K
(
A1 Journal article – refereed)

MARKED CHANGES IN (P,T) ANALYZING POWERS FOR THE ISOTOPES OF ZR, MO, RU, AND PD AND STRONG, SEQUENTIAL, 2-STEP TRANSFER PROCESSES IN BOTH (P,T) AND (T,P) REACTIONS (1982)
Physical Review C
AOKI Y, IIDA H, KUNORI S, NAGANO K, TOBA Y, YAGI K
(
A1 Journal article – refereed)

STRONG SEQUENTIAL TRANSFER PROCESSES IN 0+-]0+ (P,T) REACTIONS ON PB ISOTOPES (1981)
Physics Letters B
TOBA Y, AOKI Y, IIDA H, KUNORI S, NAGANO K, YAGI K
(
A1 Journal article – refereed)


Last updated on 2019-21-01 at 16:04