Mika Scheinin
MD, PhD, Professor Emeritus

Senior Advisor, Institute of Biomedicine (Institute of Biomedicine)

mschein@utu.fi
+358 40 501 4762

Kiinamyllynkatu 10
Turku





Areas of expertise
Bioanalytics; Clinical Pharmacology; Drug Development; Positron Emission Tomography; Research Ethics

Publications
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Effects of vatinoxan on cardiorespiratory function and gastrointestinal motility during constant-rate medetomidine infusion in standing horses (2019)
Equine Veterinary Journal
Tapio H., Raekallio M., Mykkänen A., Männikkö S., Scheinin M., Bennett R., Vainio O.
(
A1 Journal article – refereed)

Intranasal naloxone rapidly occupies brain mu-opioid receptors in human subjects (2019)
Neuropsychopharmacology
Jarkko Johansson, Jussi Hirvonen, Zsófia Lovró, Laura Ekblad, Valtteri Kaasinen, Olli Rajasilta, Semi Helin, Jouni Tuisku, Saija Sirén, Mirka Pennanen, Arvind Agrawal, Roger Crystal, Petri J. Vainio, Hannu Alho, Mika Scheinin
(
A1 Journal article – refereed)

Premedication with intranasal dexmedetomidine decreases thiopental requirements in sedation of pediatric patients for magnetic resonance imaging: a retrospective study (2019)
BMC Anesthesiology
Uusalo Panu, Lehtinen Mirjam, Löyttyniemi Eliisa, Manner Tuula, Scheinin Mika, Saari Teijo I.
(
A1 Journal article – refereed)

Radiosynthesis and Preclinical Evaluation of an α2A-Adrenoceptor Tracer Candidate, 6-[18F]Fluoro-marsanidine (2019)
Molecular Imaging and Biology
Krzyczmonik A., Keller T., López-Picón F., Forsback S., Kirjavainen A.K., Takkinen J.S., Wasilewska A., Scheinin M., Haaparanta-Solin M., Solin O.
(
A1 Journal article – refereed)

Adrenergisten reseptorien agonistit (sympatomimeetit) (2018) Farmakologia ja toksikologia Scheinin. Mika
(
D2 Article in a professional research book)

Alzheimerin taudin lääkekehityksen strategiat (2018)
Duodecim
Scheinin M, Rinne JO
(
D1 Article in a trade journal)

Effect of oral KETOPROFEN treatment in acute respiratory disease outbreaks in finishing pigs (2018) Outi Hälli, Minna Haimi-Hakala, Tapio Laurila, Claudio Oliviero, Elina Viitasaari, Toomas Orro, Olli Peltoniemi, Mika Scheinin, Saija Sirén, Anna Valros, Mari Heinonen
(
A1 Journal article – refereed)

Effects of dexmedetomidine and MK-467 on plasma glucose, insulin and glucagon in a glibenclamide-induced canine hypoglycaemia model (2018)
Veterinary Journal
Kallio-Kujala I., Bennett R., Raekallio M., Yatkin E., Meierjohann A., Savontaus E., Scheinin M., Spillmann T., Vainio O.
(
A1 Journal article – refereed)

Effects of the peripherally acting alpha(2)-adrenoceptor antagonist MK-467 on cardiopulmonary function in sheep sedated by intramuscular administration of medetomidine and ketamine and reversed by intramuscular administration of atipamezole (2018)
American Journal of Veterinary Research
Adam M, Raekallio MR, Salla KM, Honkavaara JM, Mannikko S, Scheinin M, Kajula M, Molsa SH, Vainio OM
(
A1 Journal article – refereed)

Effects of the peripherally acting α2-adrenoceptor antagonist MK-467 on cardiopulmonary function in sheep sedated by intramuscular administration of medetomidine and ketamine and reversed by intramuscular administration of atipamezole (2018)
American Journal of Veterinary Research
Kajula M., Scheinin M., Vainio O., Mölsä S., Adam M., Raekallio M., Salla K., Honkavaara J., Männikkö S.
(
A1 Journal article – refereed)

Increased Energy Expenditure, Lipolysis and Hyperinsulinemia Confer Resistance to Central Obesity and Type 2 Diabetes in Mice Lacking Alpha2α-Adrenoceptors (2018)
Neuroendocrinology
Ruohonen S, Valve L, Tuomainen K, Ailanen L, Röyttä M, Manz G, Baur N, Joos T, Savontaus E, Scheinin M
(
A1 Journal article – refereed)

Lääkeaineiden sitoutuminen reseptoriin (2018) Farmakologia ja toksikologia Scheinin M
(
D2 Article in a professional research book)

Lääkeaineiden vaikutusmekanismit: reseptorit (2018) Farmakologia ja toksikologia Scheinin. Mika
(
D2 Article in a professional research book)

Peripheral α2-adrenoceptor antagonism affects the absorption of intramuscularly coadministered drugs (2018)
Veterinary Anaesthesia and Analgesia
Ira J. Kallio-Kujala, Marja R. Raekallio, Juhana Honkavaara, Rachel C. Bennett, Heta Turunen, Mika Scheinin, Heidi Hautajärvi, Outi Vainio
(
A1 Journal article – refereed)

Sedative Plasma Concentrations and Delirium Risk in Critical Illness (2018)
Annals of Pharmacotherapy
Joanna L. Stollings, Jennifer L. Thompson, Benjamin A. Ferrell, Mika Scheinin, Grant R. Wilkinson, Christopher G. Hughes, Ayumi K. Shintani, E. Wesley Ely, Timothy D. Girard, Pratik P. Pandharipande, Mayur B. Patel
(
A1 Journal article – refereed)

Subcutaneously administered dexmedetomidine is efficiently absorbed and is associated with attenuated cardiovascular effects in healthy volunteers (2018)
European Journal of Clinical Pharmacology
P. Uusalo, D. Al-Ramahi, I. Tilli, R. A. Aantaa, M. Scheinin, T. I. Saari
(
A1 Journal article – refereed)

The impact of MK-467 on plasma drug concentrations, sedation and cardiopulmonary changes in sheep treated with intramuscular medetomidine and atipamezole for reversal (2018)
Journal of Veterinary Pharmacology and Therapeutics
M. Adam, M. R. Raekallio, T. Keskitalo, J. M. Honkavaara, M. Scheinin, M. Kajula, S. Mölsä, O. M. Vainio
(
A1 Journal article – refereed)

Cardiovascular effects of premedication with medetomidine alone and in combination with MK-467 or glycopyrrolate in dogs subsequently anesthetized with isoflurane (2017)
American Journal of Veterinary Research
Salla KM, Tuns CI, Bennett RC, Raekallio MR, Scheinin M, Kuusela E, Vainio OM
(
A1 Journal article – refereed)

Effects of the α2-adrenoceptor agonist medetomidine on the distribution and clearance of alfaxalone during coadministration by constant rate infusion in dogs (2017)
American Journal of Veterinary Research
Bennett RC, Salla KM, Raekallio MR, Scheinin M, Vainio OM
(
A1 Journal article – refereed)

Gene expression profiles and signaling mechanisms in α2B-adrenoceptor-evoked proliferation of vascular smooth muscle cells (2017)
BMC Systems Biology
Anna Huhtinen, Vesa Hongisto, Asta Laiho, Eliisa Löyttyniemi, Dirk Pijnenburg, Mika Scheinin
(
A1 Journal article – refereed)


Last updated on 2019-20-07 at 02:22