Olli Tenovuo
MD, PhD, Adj. Prof. of Neurology and Neurotraumatology

Adjunct Professor, Faculty of Medicine (Faculty of Medicine)
Clinical Lecturer, Neurology (Department of Clinical Medicine)
Department of Neurosciences
ollten@utu.fi


Kiinamyllynkatu 4-8 bld. 9 3rd floor





Areas of expertise
traumatic brain injury; rehabilitation; biomarkers; imaging

Biography

I have a long and profound experience in the field of traumatic brain injuries (TBIs), both clinically and scientifically. Patients with TBI of different severities have been my main clinical interest since early 1990’s, and during the years I have treated about 6 000 patients with TBI. Since 1996 I have led a multidisciplinary research group on TBIs, which has expanded steadily. Currently our group includes > 30 researchers, 20 of which are PhD students and 7 are post docs. They represent widely different disciplines, such as neurosurgery, neurology, neuroanaesthesiology, neuroradiology, neuropsychology, clinical neurophysiology, psychiatry etc. I have conducted also large international research projects and am currently in a leading position in several trials. I have also experience on RCTs on the field. My group has a wide collaborative network both nationally and internationally, both in experimental and clinical research. Currently we have active research collaboration with ten national and 22 international (from 13 countries) research groups.



Research

The research of our TBI has included topics from various disciplines, from psychiatry and neuropsychology to epidemiology, neurosurgery, and biochemistry. During the recent years we have mainly focused in three areas: 1) blood-based brain injury biomarkers, 2) novel brain imaging methodologies, and 3) multifaceted approach to diagnostic and prognostic modeling of TBI. We aim at solving clinical problems and conducting research which is easily transferred to clinical practice. We also collaborate with basic science in order to reveal brain injury mechanisms, since these help in understanding clinical phenomena and in developing new interventions. International collaboration and co-work are an essential part of our research policy.



Teaching

Teaching about TBI has been a major part of my work for almost 20 years, both for medical students at the Turku University as well as nationally and internationally. Annually I have about 160 hrs of teaching for medical students.



Publications
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A Decision Support System for Diagnostics and Treatment Planning in Traumatic Brain Injury (2019)
IEEE Journal of Biomedical and Health Informatics
Umer A, Mattila J, Liedes H, Koikkalainen J, Lotjonen J, Katila A, Frantzen J, Newcombe V, Tenovuo O, Menon D, van Gils M
(
A1 Journal article – refereed)

Correlation of blood biomarkers and biomarker panels with traumatic findings on computed tomography after traumatic brain injury (2019)
Journal of Neurotrauma
Posti JP, Takala RS, Lagerstedt L, Dickens AM, Hossain I, Mohammadian M, Ala-Seppälä HM, Frantzén J, Van Gils M, Hutchinson PJ, Katila AJ, Maanpää HR, Menon D, Newcombe V, Tallus J, Hrusovsky K, Wilson D, Gill J, Sanchez JC, Tenovuo O, Zetterberg H, Blennow K.
(
A1 Journal article – refereed)

Development of a quality indicator set to measure and improve quality of ICU care for patients with traumatic brain injury (2019)
Critical Care
Huijben JA, Wiegers EJA, Keizer NF, Maas AIR, Menon D, Ercole A, Citerio G, Lecky F, Wilson L, Cnossen MC, Polinder S, Steyerberg EW, Jagt MD, Lingsma HF, Aries M, Badenes R, Beishuizen A, Bilotta F, Chieregato A, Cingolani E, Cnossen M, Coburn M, Coles JP, Delargy M, Depreitere B, Flaatten H, Golyk V, Grauwmeijer E, Haitsma I, Helbok R, Hoedemaekers C, Jacobs B, Jellema K, Koskinen LOD, Maegele M, Delgado MCM, Moller K, Moreno R, Nelson D, Oldenbeuving AW, Payen JF, Pejakovic J, Ribbbers GM, Rossaint R, Schoonman GG, Steiner LA, Stocchetti N, Silvio F, Takala R, Tenovuo O, Valeinis E, van den Bergh WM, van Essen T, van Leeuwen N, Verhofstad MHJ, Vos PE; Group Author(s): Delphi Panel
(
A1 Journal article – refereed)

Early Levels of Glial Fibrillary Acidic Protein and Neurofilament Light Protein in Predicting the Outcome of Mild Traumatic Brain Injury (2019)
Journal of Neurotrauma
Hossain I, Mohammadian M, Takala RSK, Tenovuo O, Lagerstedt L, Ala-Seppälä H, Frantzén J, van Gils M, Hutchinson P, Katila AJ, Maanpää HR, Menon DK, Newcombe VF, Tallus J, Hrusovsky K, Wilson DH, Blennow K, Sanchez JC, Zetterberg H, Posti JP
(
A1 Journal article – refereed)

Randomized Controlled Trials of Rehabilitation Services in the Post-acute Phase of Moderate and Severe Traumatic Brain Injury - A Systematic Review (2019)
Frontiers in Neurology
Cecilie Røe, Cathrine Tverdal, Emilie Isager Howe, Olli Tenovuo, Philippe Azouvi, Nada Andelic
(
A2 Review article in a scientific journal)

Risk factors for recurrent hematomas after surgery for acute traumatic subdural hematoma. (2019)
World Neurosurgery
Heino Iiro, Frantzén Janek, Rinne Jaakko, Girard Romuald, Cao Ying, Sajanti Antti, Katila Ari J., Posti Jussi P., Takala Riikka S.K., Tenovuo Olli, Koskimäki Janne
(
A1 Journal article – refereed)

Serum Neurofilament Light Is Elevated Differentially in Older Adults with Uncomplicated Mild Traumatic Brain Injuries (2019)
Journal of Neurotrauma
Iverson GL, Reddi PJ, Posti JP, Kotilainen AK, Tenovuo O, Ohman J, Zetterberg H, Blennow K, Luoto TM
(
A1 Journal article – refereed)

Association between parent mental health and paediatric TBI: epidemiological observations from the 1987 Finnish Birth Cohort (2018)
Injury Prevention
Lowery Wilson M, Tenovuo O, Gissler M, Saarijärvi S
(
A1 Journal article – refereed)

Brain Cholinergic Function and Response to Rivastigmine in Patients With Chronic Sequels of Traumatic Brain Injury: A PET Study (2018)
Journal of Head Trauma Rehabilitation
Anna Östberg, Jere Virta, Juha O. Rinne, Vesa Oikonen, Pauliina Luoto, Kjell Någren, Eveliina Arponen, Olli Tenovuo
(
A1 Journal article – refereed)

Comparing disability between traumatic brain injury and spinal cord injury using the 12-item WHODAS 2.0 and the WHO minimal generic data set covering functioning and health (2018)
Clinical Rehabilitation
Sinikka Tarvonen-Schröder, Olli Tenovuo, Anne Kaljonen, Katri Laimi
(
A1 Journal article – refereed)

Comparison of Performance of Different Optimal Cerebral Perfusion Pressure Parameters for Outcome Prediction in Adult Traumatic Brain Injury: A Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) Study (2018)
Journal of Neurotrauma
Zeiler F.A., Ercole A., Cabeleira M., Carbonara M., Stocchetti N., Menon D.K., Smielewski P., Czosnyka M., Anke A., Beer R., Bellander B.M., Buki A., Chevallard G., Chieregato A., Citerio G., Czeiter E., Depreitere B., Eapen G., Frisvold S., Helbok R., Jankowski S., Kondziella D., Koskinen L.O., Meyfroidt G., Moeller K., Nelson D., Piippo-Karjalainen A., Radoi A., Ragauskas A., Raj R., Rhodes J., Rocka S., Rossaint R., Sahuquillo J., Sakowitz O., Stevanovic A., Sundström N., Takala R., Tamosuitis T., Tenovuo O., Vajkoczy P., Vargiolu A., Vilcinis R., Wolf S., Younsi A.
(
A1 Journal article – refereed)

Connectivity analysis of full montage EEG in traumatic brain injury patients in the ICU (2018)
IFMBE proceedings
EMBEC & NBC 2017. Joint Conference of the European Medical and Biological Engineering Conference (EMBEC) and the Nordic-Baltic Conference on Biomedical Engineering and Medical Physics (NBC), Tampere, Finland, June 2017 Tarmo Lipping, Niko Erkintalo, Mika Särkelä, Riikka S. K. Takala, Ari Katila, Janek Frantzén, Jussi Posti, Markus Müller, Olli Tenovuo
(
A4 Article in conference proceedings)

Cranioplasty After Severe Traumatic Brain Injury: Effects of Trauma and Patient Recovery on Cranioplasty Outcome (2018)
Frontiers in Neurology
Jussi P. Posti, Matias Yli-Olli, Lauri Heiskanen, Kalle M. J. Aitasalo, Jaakko Rinne, Ville Vuorinen, Willy Serlo, Olli Tenovuo, Pekka K. Vallittu, Jaakko M. Piitulainen
(
A1 Journal article – refereed)

Digital Gaming for Improving the Functioning of People With Traumatic Brain Injury: Randomized Clinical Feasibility Study (2018)
Journal of Medical Internet Research
Maritta Välimäki, Kaisa Mishina, Johanna K Kaakinen, Suvi K Holm, Jukka Vahlo, Markus Kirjonen, Virve Pekurinen, Olli Tenovuo, Jyrki Korkeila, Heikki Hämäläinen, Jaana Sarajuuri, Pekka Rantanen, Tage Orenius, Aki Koponen
(
A1 Journal article – refereed)

Head trauma in sports – clinical characteristics, epidemiology and biomarkers (2018)
Journal of Internal Medicine
Zetterberg H., Winblad B., Bernick C., Yaffe K., Majdan M., Johansson G., Newcombe V., Nyberg L., Sharp D., Tenovuo O., Blennow K., Blennow K.
(
A2 Review article in a scientific journal)

Mortality after traumatic brain injury and the effect of posttraumatic epilepsy (2018)
Neurology
Uski J., Lamusuo S., Teperi S., Löyttyniemi E., Tenovuo O.
(
A1 Journal article – refereed)

Practitioners’ opinions on traumatic brain injury care pathways in Finland and France: different organizations, common issues (2018)
Brain Injury
Jourdan C., Bahrami S., Azouvi P., Tenovuo O.
(
A1 Journal article – refereed)

Quantitative EEG parameters for prediction of outcome in severe traumatic brain injury: Development study (2018)
Clinical EEG and Neuroscience
Antti Tolonen, Mika O. K. Särkelä, Riikka S. K. Takala, Ari Katila, Janek Frantzén, Jussi P. Posti, Markus Müller, Mark van Gils, Olli Tenovuo
(
A1 Journal article – refereed)

Serum Metabolites Associated with Computed Tomography Findings after Traumatic Brain Injury (2018)
Journal of Neurotrauma
Dickens AM, Posti JP, Takala RSK, Ala-Seppala H, Mattila I, Coles JP, Frantzen J, Hutchinson PJ, Katila AJ, Kyllonen A, Maanpaa HR, Newcombe V, Outtrim J, Tallus J, Carpenter KLH, Menon DK, Hyotylainen T, Tenovuo O, Oresic M, Oresic M
(
A1 Journal article – refereed)


Last updated on 2019-16-09 at 02:21