Tove Grönroos
PhD, Adjunct Professor

Adjunct Professor, Department of Clinical Medicine (Department of Clinical Medicine)
Senior Research Fellow, PET Basic Operations (Turku PET Centre)

tovgro@utu.fi
+358 29 450 3839
+358 50 356 2822

Tykistökatu 6
Turku

ORCID identifier: https://orcid.org/344680805




Areas of expertise
PET, cancer, metabolism, hypoxia, inflammation, experimental radiotherapy

Research
Over 60 publications and reviews in international peer-reviewed journals from subjects including imaging of cancer, diabetes, brain and cardiology with special emphasis on molecular imaging and preclinical evaluation of new tracers for positron emission tomography. One published educational book chapter on imaging of hypoxia. Personal research interests within imaging of the tumor microenvironment, especially hypoxia, inflammation, glycolysis, amino acid transport and to image microenvironmental changes in tumors during RT treatment.

Publications
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Dovitinib dilactic acid reduces tumor growth and tumor-induced bone changes in an experimental breast cancer bone growth model (2019)
Journal of Bone Oncology
Tiina E. Kähkönen, Johanna M. Tuomela , Tove J. Grönroos, Jussi M. Halleen, Kaisa K. Ivaska , Pirkko L. Härkönen
(
A1 Journal article – refereed)

Synthesis of an Alkyne-Modified Bleomycin Disaccharide Precursor, Conversion to a F-18-Labeled Radiotracer, and Preliminary in vivo-PET Imaging Studies (2019)
European Journal of Organic Chemistry
Sajal K. Maity, Cheng-Bin Yim, Satish Jadhav, Alejandra Verhassel, Johanna Tuomela, Olof Solin, Tove J. Grönroos, Pasi Virta
(
A1 Journal article – refereed)

Fat Grafting Can Induce Browning of White Adipose Tissue (2018) Hoppela E, Gronroos TJ, Saarikko AM, Tervala TV, Kauhanen S, Nuutila P, Kivinen K, Hartiala P
(
A1 Journal article – refereed)

Molecular design of radiocopper-labelled Affibody molecules (2018)
Scientific Reports
Tolmachev V, Gronroos TJ, Yim CB, Garousi J, Yue Y, Grimm S, Rajander J, Perols A, Haaparanta-Solin M, Solin O, Ferdani R, Orlova A, Anderson CJ, Karlstrom AE
(
A1 Journal article – refereed)

Repeatability of tumour hypoxia imaging using [18F]EF5 PET/CT in head and neck cancer (2018)
European Journal of Nuclear Medicine and Molecular Imaging
Antti Silvoniemi, Sami Suilamo, Timo Laitinen, Sarita Forsback, Eliisa Löyttyniemi, Samuli Vaittinen, Virva Saunavaara, Olof Solin, Tove J. Grönroos, Heikki Minn
(
A1 Journal article – refereed)

Reversibility of myocardial metabolism and remodelling in morbidly obese patients 6 months after bariatric surgery (2018)
Diabetes, Obesity and Metabolism
Hannukainen JC, Lautamäki R, Pärkkä J, Strandberg M, Saunavaara V, Hurme S, Soinio M, Dadson P, Virtanen KA, Grönroos T, Forsback S, Salminen P, Iozzo P, Nuutila P
(
A1 Journal article – refereed)

Comparative Evaluation of Anti-HER2 Affibody Molecules Labeled with Cu-64 Using NOTA and NODAGA (2017)
Contrast Media and Molecular Imaging
Vladimir Tolmachev, Cheng-Bin Yim, Johan Rajander, Anna Perols, Amelie Eriksson Karlström, Merja Haaparanta-Solin, Tove J. Grönroos, Olof Solin, Anna Orlova
(
A1 Journal article – refereed)

HPLC and TLC methods for analysis of [F-18]FDG and its metabolites from biological samples (2017)
Journal of Chromatography B
Johanna Rokka, Tove J. Grönroos, Tapio Viljanen, Olof Solin,Merja Haaparanta-Solin
(
A1 Journal article – refereed)

Lipid Bilayer-Gated Mesoporous Silica Nanocarriers for Tumor-Targeted Delivery of Zoledronic Acid in Vivo. (2017)
Molecular Pharmaceutics
Diti Desai, Jixi Zhang, Jouko Sandholm, Jaakko Lehtimäki, Tove Grönroos, Johanna Tuomela, and Jessica M. Rosenholm
(
A1 Journal article – refereed)

Two weeks of moderate-intensity continuous training, but not high-intensity interval training, increases insulin-stimulated intestinal glucose uptake (2017)
Journal of Applied Physiology
Motiani KK, Savolainen AM, Eskelinen JJ, Toivanen J, Ishizu T, Yli-Karjanmaa M, Virtanen KA, Parkkola R, Kapanen J, Gronroos TJ, Haaparanta-Solin M, Solin O, Savisto N, Ahotupa M, Löyttyniemi E, Knuuti J, Nuutila P, Kalliokoski KK, Hannukainen JC
(
A1 Journal article – refereed)

Ex Vivo Tracing of NMDA and GABA-A Receptors in Rat Brain After Traumatic Brain Injury Using F-18-GE-179 and F-18-GE-194 Autoradiography (2016)
Journal of Nuclear Medicine
Lopez-Picon F, Snellman A, Shatillo O, Lehtiniemi P, Gronroos TJ, Marjamaki P, Trigg W, Jones PA, Solin O, Pitkanen A, Haaparanta-Solin M
(
A1 Journal article – refereed)

Increased striatal VMAT2 binding in mice after chronic administration of methcathinone and manganese (2016)
Brain Research
Asser A, Kõks S, Snellman A, Haaparanta-Solin M, Arponen E, Grönroos T, Nairismägi J, Bergquist J, Soomets U, Piip P, Eltermaa M, Sauk M, Lindmäe H, Rinne JO, Taba P.
(
A1 Journal article – refereed)

Inhibiting Notch Activity in Breast Cancer Stem Cells by Glucose Functionalized Nanoparticles Carrying gamma-secretase Inhibitors (2016)
Molecular Therapy
Mamaeva V, Niemi R, Beck M, Ozliseli E, Desai D, Landor S, Gronroos T, Kronqvist P, Pettersen IKN, McCormack E, Rosenholm JM, Linden M, Sahlgren C
(
A1 Journal article – refereed)

PET of EGFR with 64Cu-cetuximab-F(ab')2 in mice with head and neck squamous cell carcinoma xenografts (2016)
Contrast Media and Molecular Imaging
van Dijk LK, Yim CB, Franssen GM, Kaanders JH, Rajander J, Solin O, Grönroos TJ, Boerman OC, Bussink J
(
A1 Journal article – refereed)

Solid-supported porphyrins useful for the synthesis of conjugates with oligomeric biomolecules (2016)
Bioconjugate Chemistry
Satish Jadhav, Cheng-Bin Yim, Johan Rajander, Tove J. Grönroos, Olof Solin, Pasi Virta
(
A1 Journal article – refereed)

6-[18F]Fluoro-l-DOPA Uptake in the Rat Pancreas is Dependent on the Tracer Metabolism (2014)
Molecular Imaging and Biology
Kalliokoski T, Tuomela J, Haavisto L, Forsback S, Snellman A, Helin S, Gronroos TJ, Solin O, Haaparanta-Solin M
(
A1 Journal article – refereed)

Analysis of Fat Graft Metabolic Adaptation and Vascularization Using Positron Emission Tomography–Computed Tomographic Imaging (2014)
Plastic and Reconstructive Surgery
Tervala TV, Grönroos TJ, Hartiala P, Nuutila P, Suominen EA, Karra H, Kivinen K, Ylä-Herttuala S, Saarikko AM
(
A1 Journal article – refereed)

A PET Tracer for Brain α2C Adrenoceptors, 11C-ORM-13070: Radiosynthesis and Preclinical Evaluation in Rats and Knockout Mice (2014)
Journal of Nuclear Medicine
Arponen E, Helin S, Marjamäki P, Grönroos T, Holm P, Löyttyniemi E, Någren K, Scheinin M, Haaparanta-Solin M, Sallinen J, Solin O
(
A1 Journal article – refereed)

Evaluation of repeated [18F]EF5 PET/CT scans and tumor growth rate in experimental head and neck carcinomas (2014)
EJNMMI Research
Silvoniemi Antti, Silén Jonna, Forsback Sarita, Löyttyniemi Eliisa, Schrey Aleksi R, Solin Olof, Grénman Reidar, Minn Heikki, Grönroos Tove J
(
A1 Journal article – refereed)

FDG-PET in HeaIthy and Epileptic Lagotto Romagnolo Dogs and Changes in Brain Glucose Uptake with Age (2014)
Veterinary Radiology and Ultrasound
Jokinen TS, Haaparanta-Solin M, Viitmaa R, Grönroos TJ, Johansson J, Bergamasco L, Snellman M, Metsähonkala L
(
A1 Journal article – refereed)


Last updated on 2019-26-08 at 02:21