Päivi Lähteenmäki
MD, PhD Docent (Adjunct professor); Medicine (Department of Clinical Medicine)

Adjunct Professor, Department of Clinical Medicine (Department of Clinical Medicine)

palahte@utu.fi







Areas of expertise
Pediatric and adolescent hematology and oncology; Late-effects of cancer treatment at an early age; Quality improvement and registration.

Biography



Päivi Lähteenmäki graduated from the Medical School at the University of Turku in 1984, where she also specialized in Pediatrics and
PediatricHematology and Oncology. She defended her thesis in 1999 on Effects of
childhood cancer on patients and their families - physical and psychosocial
aspects. She worked in 2002 as a post-doc Clinical and Research Fellow at Bristol Sick Children’s Hospital BMT
Unit, Bristol, UK. Subsequently, she has
worked as a Consultant at the Department of Pediatrics, University of Turku.
Since 2008, she has been Docent (Adjunct Professor) of Pediatric Hematology and
Oncology at the Faculty of Medicine, University of Turku, and Head of the Division of Pediatric
and Adolescent Hematology/Oncology at Turku University Hospital in Turku,
Finland. Currently she works also as the Chief of the Swedish Childhood Cancer
Registry at Karolinska Institutet in Stockholm, Sweden.

During the
years, Päivi Lähteenmäki has served as the chairman or a board member of the Nordic Society of Pediatric Hematology and Oncology as well as the
Finnish Association of Pediatric Hematology and Oncology. In 2012-2014, She was the chair of
a group planning the establishment of childhood cancer late-effect clinics in
Finland. In 2016, she was awarded the Finnish Cancer Association Price, Oncologist
of the year in Finland.



Research



Päivi
Lähteenmäki´s major
research interest lies in the late-effects of childhood cancer. In year 2000, she
founded her own research group and initiated a long-term research project called
“Health and Quality of Life in Patients with Early Age Onset Cancer” including
the epidemiology, diagnosis, prevention, and overall societal impact of the
late sequelae of cancer and its treatments. Päivi Lähteenmäki
has been actively involved in international research collaboration. In 2006, she
started a collaboration with NIH funded GCCT (Genetic consequences of cancer
therapies) consortium, followed by a Nordic project ALiCCS (Adult life in
childhood cancer survivors), and an EU funded project PanCareSurFup (PanCare
Childhood and Adolescent Cancer Survivor Care and Follow-Up Studies). In 2018,
two new Nordic collaborations started (PACCS Physical activity in childhood
cancer survivors; PACS Pregnancy associated cancer). She is also a principal
investigator in NOPHO-CARE (A Nordic study on epidemiology, biology, treatment
and survival of children with cancer and severe hematological diseases).



Teaching



Since 2008, clinical pediatric hematology and oncology at the Department
of Pediatrics and Adolescent Medicine, University of Turku.



Publications
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Asparaginase treatment in infants with acute lymphoblastic leukemia; pharmacokinetics and asparaginase hypersensitivity in Interfant-06 (2019)
Leukemia and Lymphoma
Albertsen BK, Harila-Saari A, Jahnukainen K, Lahteenmaki P, Riikonen P, Mottonen M, Lausen B
(
A1 Journal article – refereed)

Genetic predisposition to PEG-asparaginase hypersensitivity in children treated according to NOPHO ALL2008 (2019)
British Journal of Haematology
Sofie G. Højfeldt, Benjamin O. Wolthers, Morten Tulstrup, Jonas Abrahamsson, Ramneek Gupta, Arja Harila-Saari, Mats Heyman, Louise T. Henriksen, Òlafur G. Jónsson, Päivi M. Lähteenmäki, Bendik Lund, Kaie Pruunsild, Goda Vaitkeviciene, Kjeld Schmiegelow, Birgitte K. Albertsen; on behalf of the Nordic Society of Paediatric Haematology Oncology (NOPHO) group
(
A1 Journal article – refereed)

Lapsuuden aivokasvaimen myöhäisvaikutukset (2019)
Lääkärilehti
Storm Erika, Lähteenmäki Päivi, Lähdesmäki Tuire
(
A2 Review article in a scientific journal)

Risk of subsequent primary leukaemias among 69,460 five-year survivors of childhood cancer diagnosed from 1940 to 2008 in Europe: A cohort study within PanCareSurFup (2019)
European Journal of Cancer
Allodji RS, Hawkins MM, Bright CJ, Fidler-Benaoudia MM, Winter DL, Alessi D, Fresneau B, Journy N, Morsellino V, Bardi E, Bautz A, Byrne J, Feijen EAM, Teepen JC, Vu-Bezin G, Rubino C, Garwicz S, Grabow D, Gudmundsdottir T, Guha J, Hau EM, Jankovic M, Kaatsch P, Kaiser M, Linge H, Muraca M, Llanas D, Veres C, Ofstaas H, Diallo I, Mansouri I, Ronckers CM, Skinner R, Terenziani M, Wesenberg F, Wiebe T, Sacerdote C, Jakab Z, Haupt R, Lahteenmaki P, Zaletel LZ, Kuehni CE, Winther JF, Michel G, Kremer LCM, Hjorth L, Haddy N, de Vathaire F, Reulen RC, Reulen RC
(
A1 Journal article – refereed)

Sweden and Finland need to improve the support provided for the siblings of children with cancer (2019)
Acta Paediatrica
Malin Lövgren, Nina Mogensen, Arja Harila‐Saari, Päivi Maria Lähteenmäki, Ulrika Kreicbergs
(
A1 Journal article – refereed)

Bone mineral density is compromised in very long-term survivors of irradiated childhood brain tumor (2018)
Acta Oncologica
Tiina M. Remes, Pekka M. Arikoski, Päivi M. Lähteenmäki, Mikko O. Arola, Tytti M.-L. Pokka, V. Pekka Riikonen, Kirsti H. Sirkiä, Heikki M. J. Rantala, Arja H. Harila-Saari, Marja K. Ojaniemi
(
A1 Journal article – refereed)

Lapsena syövän sairastaneiden myöhäisseurannassa yhtenäinen perusta (2018)
Lääkärilehti
Jahnukainen Kirsi, Rantanen Niina, Mannisto Susanna, Pesola Jouni, Vuolukka Kristiina, Niinimäki Riitta, Arola Mikko, Lehtinen Tuula, Lähteenmäki Päivi
(
D1 Article in a trade journal)

Late vertebral side effects in long-term survivors of irradiated childhood brain tumor (2018)
PLoS ONE
Miro-Pekka Jussila, Tiina Remes, Julia Anttonen, Arja Harila-Saari, Jaakko Niinimäki, Tytti Pokka, Päivi Koskenkorva, Anna Sutela, Sanna Toiviainen-Salo, Pekka Arikoski, Pekka Riikonen, Mikko Arola, Päivi Lähteenmäki, Kirsti Sirkiä, Heikki Rantala, Maria Suo-Palosaari, Marja Ojaniemi
(
A1 Journal article – refereed)

Long-term clinical and economic outcomes in previously untreated paediatric patients with severe haemophilia A: A nationwide real-world study with 700 person-years (2018)
Haemophilia
K. Vepsäläinen, P. Riikonen, R. Lassila, M. Arola, P. Huttunen, P. Lähteenmäki, M. Möttönen, T. Selander, J. Martikainen
(
A1 Journal article – refereed)

Risk of Subsequent Bone Cancers Among 69 460 Five-Year Survivors of Childhood and Adolescent Cancer in Europe (2018)
JNCI: Journal of the National Cancer Institute
Fidler M., Reulen R., Winter D., Allodji R., Bagnasco F., Bárdi E., Bautz A., Bright C., Byrne J., Feijen E., Garwicz S., Grabow D., Gudmundsdottir T., Guha J., Haddy N., Jankovic M., Kaatsch P., Kaiser M., Kuonen R., Linge H., Maule M., Merletti F., Øfstaas H., Ronckers C., Skinner R., Teepen J., Terenziani M., Vu-Bezin G., Wesenberg F., Wiebe T., Jakab Z., Haupt R., Lähteenmäki P., Zaletel L., Kuehni C., Winther J., de Vathaire F., Kremer L., Hjorth L., Hawkins M.
(
A1 Journal article – refereed)

The PanCareSurFup cohort of 83,333 five-year survivors of childhood cancer: a cohort from 12 European countries (2018)
European Journal of Epidemiology
Desiree Grabow, Melanie Kaiser, Lars Hjorth, Julianne Byrne, Daniela Alessi, Rodrigue S. Allodji, Francesca Bagnasco, Edit Bárdi, Andrea Bautz, Chloe J. Bright, Florent de Vathaire, Elizabeth A. M. Feijen, Stanislaw Garwicz, Oskar Hagberg, Riccardo Haupt, Mike M. Hawkins, Zsuzsanna Jakab, Leontien C. M. Kremer, Claudia E. Kuehni, Rahel Kuonen, Päivi Maria Lähteenmäki, Raoul C. Reulen, Cécile M. Ronckers, Carlotta Sacerdote, Giao Vu-Bezin, Finn Wesenberg, Thomas Wiebe, David L. Winter, Jeanette Falck Winther, Lorna Zadravec Zaletel, Peter Kaatschon; behalf of the PanCareSurFup Consortium
(
A1 Journal article – refereed)

The PanCareSurFup consortium: research and guidelines to improve lives for survivors of childhood cancer (2018)
European Journal of Cancer
Julianne Byrne, Daniela Alessi, Rodrigue S. Allodji, Francesca Bagnasco, Edit Bárdi, Andrea Bautz, Chloe J. Bright, Morven Brown, Ibrahima Diallo, Elizabeth A.M. (Lieke) Feijen, Miranda M. Fidler, Eva Frey, Stanislaw Garwicz, Desiree Grabow, Thorgerdur Gudmundsdottir, Oskar Hagberg, Arja Harila-Saari, Eva M. Hau, Riccardo Haupt, Mike M. Hawkins, Zsuzsanna Jakab, Momcilo Jankovic, Peter Kaatsch, Melanie Kaiser, Leontien C.M. Kremer, Claudia E. Kuehni, Rahel Kuonen, Ruth Ladenstein, Päivi Maria Lähteenmäki, Gill Levitt, Helena Linge, Damien LLanas, Gisela Michel, Vera Morsellino, Renee L. Mulder, Raoul C. Reulen, Cécile M. Ronckers, Carlotta Sacerdote, Roderick Skinner, Eva Steliarova-Foucher, Helena J.van der Pal, Florentde Vathaire, Giao Vũ Bezin, Finn Wesenberg, Thomas Wiebe, David L. Winter, Jeanette Falck Winther, Elise Witthoff, Lorna Zadravec Zaletel, Lars Hjorth
(
A2 Review article in a scientific journal)

Treatment-related mortality in relapsed childhood acute lymphoblastic leukemia (2018)
Pediatric Blood and Cancer
Trausti Oskarsson, Stefan Söderhäll, Johan Arvidson, Erik Forestier, Thomas Leth Frandsen, Marit Hellebostad, Päivi Lähteenmäki, Ólafur G. Jónsson, Ida Hed Myrberg, Mats Heyman; On Behalf of the Nordic Society of Paediatric Haematology and Oncology (NOPHO) ALL Relapse Working Group
(
A1 Journal article – refereed)

Yleistynyt vyöruusu (2018)
Duodecim
Ivaska L, Turta O, Peltola V, Lähteenmäki P
(
D1 Article in a trade journal)

Compulsory military service as a measure of later physical and cognitive performance in male survivors of childhood cancer (2017)
Acta Oncologica
Ritva Ahomäki, Arja Harila-Saari, Kai Parkkola, Jaakko Matomäki, Päivi M. Lähteenmäki
(
A1 Journal article – refereed)

Decreased spermatogonial quantity in prepubertal boys with leukaemia treated with alkylating agents (2017)
Leukemia
Poganitsch-Korhonen M, Masliukaite I, Nurmio M, Lähteenmäki P, van Wely M, van Pelt AMM, Jahnukainen K, Stukenborg JB
(
B1 Journal article)

Early presentation of osteonecrosis in acute lymphoblastic leukemia: Two children from the Nordic and Baltic cohort (2017)
Pediatric Blood and Cancer
Mogensen SS, Harila-Saari A, Frandsen TL, Lahteenmaki P, Castor A, Kohonen I, Schmiegelow K, Makitie O
(
A1 Journal article – refereed)

Hepatic sinusoidal obstruction syndrome during maintenance therapy of childhood acute lymphoblastic leukemia is associated with continuous asparaginase therapy and mercaptopurine metabolites (2017)
Pediatric Blood and Cancer
Toksvang LN, De Pietri S, Nielsen SN, Nersting J, Albertsen BK, Wehner PS, Rosthoj S, Lahteenmaki PM, Nilsson D, Nystad TA, Grell K, Frandsen TL, Schmiegelow K
(
A1 Journal article – refereed)

Non-graduation after comprehensive school, and early retirement but not unemployment are prominent in childhood cancer survivors—a Finnish registry-based study (2017)
Journal of Cancer Survivorship
Ritva Ahomäki, Arja Harila-Saari, Jaakko Matomäki, Päivi M. Lähteenmäki
(
A1 Journal article – refereed)

Posterior Reversible Encephalopathy Syndrome: Risk Factors and Impact on the Outcome in Children With Acute Lymphoblastic Leukemia Treated With Nordic Protocols (2017)
Journal of Pediatric Hematology/Oncology
Möttönen M., Riikonen P., Taskinen M., Lönnqvist T., Harila-Saari A., Banerjee J., Heyman M., Palomäki M., Lähteenmäki P., Arola M.
(
A1 Journal article – refereed)


Last updated on 2019-27-01 at 11:47