Projects Ph.D. Theses Front Page				Theses (by groups) Phosphorylation-Based Signaling in Cytoskeletal Regulation and Cell Survival (John Eriksson) Microcystins - Potent tools to study serine/threonine protein phosphatases and their role in cytoskeletal regulation. Diana Toivola, 1997 The role of mitogen-activated kinase in Fas receptor-mediated apoptosis. Tim Holmström, 2000 Carbohydrate Receptors and Ligands (Jukka Finne) Binding mechanism of Streptococcus suis to host cell surface carbohydrates. Sauli Haataja, 1996 Capsular polysaccharides of bacteria causing meningitis. Antibody-binding properties and cross-reactivity with tissue glycoproteins. Jukka Häyrinen, 1996 Purification and properties of a galactosyl-a1-4-galactose-binding adhesin - a potential vaccine against Streptococcus suis. Kaarina Tikkanen, 1996 Characterization of Pectinatus cerevisiiphilus and P. frisingiensis surface components. Use of synthetic peptides in the detection of some of gram-negative bacteria. Elias Hakalehto, 2000. Histaminergic Regulation of Brain Functions and Significance of RFamide Peptides in Sensory Regulation (Pertti Panula) Histamine and histidine decarboxylase in embryonic development with special reference to the oxyntic mucosa. Markku Nissinen, 1995 Histaminergic regulation of the nigrostriatal system in Parkinson's disease and a rat model of Parkinsonism. Oleg Anichtchik, 2001 Brain histamine in alcohol-related behaviours and experimental epilepsy. Minnamaija Lintunen, 2001 Development of central and peripheral histamine synthesis and receptor expression. Kaj Karlstedt, 2001 Neuropeptide FF: Neural Systems and Hypothalamic Functions. Antti A. Aarnisalo, 1998. Mechanisms of Spondyloarthropathies (Kaisa Granfors) Mononuclear phagocytes and the pathogenesis of Yersinia-triggered reactive arthritis. Maarit Wuorela, 1996. Salmonella-triggered reactive arthritis. Mononuclear cells and pathogenesis. Juha Kirveskari, 1998. Host-microbe interaction in intestinal epithelium: A special reference to arthritogenic bacteria and nitric oxide. Marja Saarinen, 1999. Host-microbe interactions in Salmonella-triggered reactive arthritis. With special reference to HLA-B27. Päivi Ekman, 2000. Collagen Receptor Integrins (Jyrki Heino) Regulation and function of collagen receptor integrins in osteosarcoma cells. Pia Vihinen, 1996. Cell adhesion receptors in rheumatoid synovial lining. Laura Pirilä, 1997. Integrin-type collagen receptors as regulators of cell behaviour and gene expression. Terhi Lehtinen, 1998. Molecular pathogenesis of echovirus-1 infection. Pasi Huttunen, 1999. Cellular collagen receptors: Different ligand recognition and signal transduction functions. Johanna Ivaska, 2000. Molecular Pharmacology of a2-Adrenergic Receptors (Mika Scheinin) a2 adrenoceptors and their role in anesthesia and spinal antinociception in the rat. Maarit Hillilä 1996. Dexmedetomidine as a preanesthetic agent - phase I-III studies with a novel, spesific a2-adrenoceptor agonist. Marja-Leena Jaakola. 1997 The a2C-adrenoceptor - a potential target for new subtype-selective drugs for use in neuropsychiatric disorders. Jukka Sallinen. 1998 Expression, production and purification of the human a2-adrenergic receptor subtype c2, a member of the G-protein coupled receptor family. Sari Liitti. 1999 Characterization of a2-adrenoceptor activation, functional assays based on transfected cells. - Turun yliopiston julkaisuja. Marjo Pihlavisto. 2000 Structural determinants of a2A-adrenoceptor ligand binding and receptor activation. Heini Frang. 2002 Cell Trafficking (Sirpa Jalkanen) Circulating form of vascular adhesion protein-1 (VAP-1). Riikka Kurkijärvi, 2004 Adhesion molecules in the dissemination and the prognosis of cancer. Special reference to CD44, VAP-1 and LYVE-1. Sanna-Mari Maula, 2003 Lymphocyte traffic and adhesion receptors in the pancreas and the gut: special emphasis on autoimmune diabetes. Ilkka Jaakkola, 2003 An immunotherapeutic approach to cancer of the head and neck. Heikki Irjala, 2002 Role of soluble mediators in leukocyte activation and adhesion to the endothelium: special emphasis on cytokine and purine mediated pathways. Tiina Henttinen, 2001 Leukocyte adhesion to endothelium in vitro and in vivo: role of vascular adhesion protein-1 (VAP-1). Sami Tohka, 2001 Vascular adhesion protein-1 as a target for anti-adhesive therapy and inflammation diagnostics. Kimmo Jaakkola, 2000 The regulation of lymphocyte trafficking: role of the multifunctional adhesion molecules VAP-1 and CD73. Anna-Maija Kujari, 1998 Lymphocyte-endothelial cell interactions: molecular analysis of vascular adhesion protein-1 (VAP-1). Petri Bono, 1998 On the role of CD73 in lymphocyte adhesion. Laura Airas, 1996 Mechanisms of lymphocyte accumulation in the endocrine pancreas in insulin-ependent diabetes. Arno Hänninen, 1995 Tissue-selective lymphocyte-endothelial cell interactions in man. Marko Salmi, 1995 Prognostic factors in non-Hodgkin's lymphoma: a special reference to CD44. Ristamäki, 1995 Matrix Metalloproteinases (Veli-Matti Kähäri) Transcriptional regulation of fibroblast collagenase (MMP-1) gene expression. Jukka Westermarck, 1997 Human collagenase-3 (MMP-13) in development and malignant transformation. Nina Johansson, 1998 Regulation of the expression of human collagenase-3 (MMP-13) - Implications for wound repair and dermal fibrosis. Laura Ravanti, 2000 Transcriptional Regulation of Heat Shock Response (Lea Sistonen) Differential functions of heat shock transcription factors 1 and 2. Lila Pirkkala, 2000. Phosphorylation-mediated regulation of heat shock transcription factor 1. Carina Holmberg, 2000.