Genome Research Programme

1994-2000

Introduction

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Themes

Funding

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RESEARCH PROJECTS

Alpha-2 receptors: Structural and bioinformatics for drug design
Coordinator Adrian Goldman (University of Turku)

Bacterial virulence genes. Structure-function relationship and pathogenetic function of gene products
Coordinator Timo Korhonen (University of Helsinki)

Bioinformational attack on superfamily modelling and drug discovery
Coordinator Mark Johnson (Åbo Akademi University)

Cross-talk of transcription factors in nuclear signaling
Coordinator Olli Jänne (University of Helsinki)

Disease resistance and wood durability in birch and aspen through gene technology
Coordinator Kim von Weissenberg (University of Helsinki)

From gene to its in vivo function
Coordinator Seppo Vainio (University of Oulu)

Functional analysis of genes and encoded proteins participating in membrane traffic/protein secretion
Coordinator Sirkka Keränen (VTT Technical Research Centre of Finland)

Genetics of multifactorial diseases
Coordinator Juha Kere (University of Helsinki)

Joint Program on disease models and gene therapy in transgenic mice
Coordinator Eero Vuorio (University of Turku)

Molecular biology and disease in associations of the Ezrin-Merlin protein family
Coordinator Antti Vaheri (University of Helsinki)

Neuropeptide FF basic mechanisms in cellular signalling as revealed by gene knockout and implications in drug development
Coordinator Pertti Panula (Åbo Akademi University)

Positioning and identification of disease loci in the post-genome era
Coordinator Leena Palotie (National Public Health Institute)

Regulation of gene expression in poikilothermic water-breathing animals: molecular adaptations to extreme environmental conditions
Coordinator Lea Sistonen (Åbo Akademi University)

Retrotransposon vectors for integration and transformation in barley
Coordinator Alan Schulman (University of Helsinki)

Structure and origin of the Finno-Ugric populations as revealed by molecular genetic analysis
Coordinator Marja-Liisa Savontaus (University of Turku)

The angiogenesis inhibitor endostatin is a fragment of type XVIII collagen
Coordinator Taina Pihlajaniemi (University of Oulu)

The role of Hrp-like proteins in the interaction between the phytopathogen Erwinia carotovora and its host plants
Coordinator Hannu Saarilahti (University of Helsinki)

The signalling genes of morphogenesis
Coordinator Hannu Sariola (University of Helsinki)

Use of replication deficient adenovirus vectors and active peptides in the prevention of vascular injury after angioplasty and coronary bypass surgery
Coordinator Pekka Häyry (University of Helsinki)

Vascular and liver gene therapy
Coordinator Seppo Ylä-Herttuala (University of Kuopio)